Biological effect of asbestos dust on the peritoneal viscera of rats

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engelbrecht_biological_1973.pdf(3.56 MB)
Date
1973-09
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Health & Medical Publishing Group
Abstract
ENGLISH ABSTRACT: Crocidolite and chrysotile asbestos suspensions were ip injected into rats. Peritoneal mesotheliomas were induced in 90% of the crocidolite group and in 30% of the chrysotile group. The pathology and possible pathogenesis are described and discussed. It is postulated that the asbestos fibers are encapsulated by fibrous tissue and that a soluble carcinogen then diffuses from these fibers to the mesothelial cells, causing anaplastic changes.
Description
CITATION: Engelbrecht, F.M. & Burger, B.F. 1973. Biological Effect of Asbestos Dust on the Peritoneal Viscera of Rats. S Afr Med J, 47(9):1746-1750.
The original publication is available at http://www.samj.org.za
Keywords
Asbestos dust, Malignancy (Cancer), Chrysotile
Citation
Engelbrecht, F.M. & Burger, B.F. 1973. Biological Effect of Asbestos Dust on the Peritoneal Viscera of Rats. S Afr Med J, 47(9):1746-1750.
URI
http://hdl.handle.net/10019.1/7770
Collections
Research Articles (Medical Physiology)