Urinary porphyrins and porphyrin precursors in normal pregnancy. Relationship to urinary total oestrogen excretion
Date
1975
Authors
De Klerk, M.
Weideman, A.
Malan, C.
Shanley, B. C.
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group (HMPG)
Abstract
The relationship between urinary excretion of porphyrins, porphyrin precursors and total oestrogens in normal pregnancy was investigated. Significant increases in total oestrogen, delta aminolaevulinic acid (ALA) and coproporphyrin (COPRO) excretion were noted. However, no close correlation was found between total oestrogen excretion and urinary output of ALA and COPRO. The results suggest that the observed increases in ALA and COPRO excretion during pregnancy may not simply be the result of steroid mediated induction of hepatic haem biosynthesis, as has been proposed.
Description
Article
The original publication is available at http://www.samj.org.za
The original publication is available at http://www.samj.org.za
Keywords
Porphyrins, Hormones in pregnancy, Porphyria -- Effect of steroid hormones on, Oestrogen secretion in pregnancy, Uroporphyrins -- Relationship -- Oestrogen secretion
Citation
De Klerk, M., Weideman, A., Malan, C. & Shanley, B.C. 1975, Urinary porphyrins and porphyrin precursors in normal pregnancy. Relationship to urinary total oestrogen excretion, SA Medical Journal, 49(14), 581-583, http://archive.samj.org.za/