Actinic granuloma-like change in exogenous ochronosis: Case report
Date
1990
Authors
Jordaan H.F.
Mulligan R.P.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Exogenous ochronosis is caused by the longterm application of skin-lightening creams containing hydroquinone. This irreversible disfiguring cosmetic problem assumes epidemic proportions in South African blacks. Mild ochronosis is characterized clinically by coarsening and darkening of the skin and severe ochronosis by coalescing, caviar-like black papules and atrophy. Histology shows ochronotic collagen fibres with eventual formation of ochronotic colloid milium. A variable cellular infiltrate, which may be granulomatous, is present. We describe a 39-year-old black woman with severe exogenous ochronosis who developed superimposed annular lesions with granulomatous histology bearing great resemblance to lesions of actinic granuloma.
Description
Keywords
hydroquinone, age, article, case report, female, granuloma, histology, human, ochronosis, priority journal, Actins, Adult, Case Report, Cell Transformation, Neoplastic, Female, Granuloma, Histocytochemistry, Human, Ochronosis, Skin Diseases
Citation
Journal of Cutaneous Pathology
17
4
17
4