Respiratory control of metabolism and gene expression: A common factor in obesity and cancer

Macfarlane C.M. (2000)


The role of oxygen deficiency, or hypoxia, in carcinogenesis is being re-discovered. This 'primitive hormone' is now known to play a vital role in gene transcription and angiogenesis. One of the most recent and promising innovations in the treatment of cancer is the hypoxia-activated triazine drugs. These drugs target hypoxic cells in solid tumours, and may prove useful in the treatment of other hyperplastic diseases.

Please refer to this item in SUNScholar by using the following persistent URL:
This item appears in the following collections: