Guideline for the prevention, diagnosis and management of cryptococcal meningitis among HIV-infected persons : 2013 update

Govender, N. P. ; Meintjies, G. ; Bicanic, T. ; Dawood, H. ; Harrison, T. S. ; Jarvis, J. N. ; Karstaedt, A. S. ; Maartens, D. ; McCarthy, K. M. ; Rabie, H. ; Variava, E. ; Venter, W. D. F. ; Boulware, D. R. ; Chiller, T. ; Meya, D. B. ; Scriven, J. (2013)

CITATION: Govender, N. P. et al. 2013. Guideline for the prevention, diagnosis and management of cryptococcal meningitis among HIV-infected persons : 2013 update. Southern African Journal of HIV Medicine, 14(2):a82, doi:10.4102/sajhivmed.v14i2.82.

The original publication is available at https://sajhivmed.org.za

Article

Six years after the first Society guidelines were published, cryptococcal meningitis (CM) remains an important cause of morbidity and mortality among HIV-infected adults in South Africa. Several important developments have spurred the publication of updated guidelines to manage this common fungal opportunistic infection. Recommendations described here include: (1) screening and pre-emptive treatment; (2) laboratory diagnosis and monitoring; (3) management of a first episode of CM; (4) amphotericin B deoxycholate toxicity prevention, monitoring and management; (5) timing of antiretroviral therapy among patients with CM; (6) management of raised intracranial pressure; (7) management of relapse episodes of CM.

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