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Now showing items 1-5 of 5

A comparison of biomarker based incidence estimators

McWalter T.A. Welte A. (2009)

Background: Cross-sectional surveys utilizing biomarkers that test for recent infection provide a convenient and cost effective way to estimate HIV incidence. In particular, the BED assay has been developed for this purpose. ...
Comparison of diagnostic criteria of tuberculous meningitis in human immunodeficiency virus-infected and uninfected children

Van Der Weert E.M. Hartgers N.M. Schaaf H.S. Eley B.S. Pitcher R.D. Wieselthaler N.A. Laubscher R. Donald P.R. Schoeman J.F. (2006)

INTRODUCTION: Tuberculous (TB) meningitis is sometimes difficult to diagnose in young children. The decision to start anti-TB treatment of TB meningitis is usually made on clinical grounds and results of special investigations, ...
Elimination of bacterial DNA from Taq DNA polymerases by restriction endonuclease digestion

Carroll N.M. Adamson P. Okhravi N. (1999)

The incidence of false positives due to the presence of bacterial DNA in Taq DNA polymerase is an obstacle to the use of PCR in the diagnosis of infection. We describe a method that uses a restriction enzyme to destroy the ...
HIV incidence in rural South Africa: Comparison of estimates from longitudinal surveillance and cross-sectional cBED assay testing

Barnighausen T. Wallrauch C. Welte A. McWalter T.A. Mbizana N. Viljoen J. Graham N. Tanser F. Puren A. Newell M.-L. (2008)

Background: The BED IgG-Capture Enzyme Immunoassay (cBED assay), a test of recent HIV infection, has been used to estimate HIV incidence in cross-sectional HIV surveys. However, there has been concern that the assay ...
Improvement in mycobacterial yield and reduced time to detection in pediatric samples by use of a nutrient broth growth supplement

Brittle W. Marais B.J. Hesseling A.C. Schaaf H.S. Kidd M. Wasserman E. Botha T. (2009)

There is an urgent need to improve the methods used for the bacteriological diagnosis of childhood mycobacterial disease. This study compared the mycobacterial yields and the times to detection (in days) of mycobacteria ...