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Complexing of the CD-3 subunit by a monoclonal antibody activates a microtubule-associated protein 2 (MAP-2) serine kinase in Jurkat cells

Hanekom C.; Nel A.; Gittinger C.; Rheeder A.; Landreth G. (1989)

Treatment of Jurkat T-cells with anti-CD-3 monoclonal antibodies resulted in the rapid and transient activation of a serine kinase with utilized the microtubule-associated protein, MAP-2, as a substrate in vitro. The kinase ...