• Identification of a novel WAS mutation in a South African patient presenting with atypical Wiskott-Aldrich syndrome : a case report 

      Glanzmann, Brigitte; Möller, Marlo; Schoeman, Mardelle; Urban, Michael; Van Helden, Paul D.; Frigati, Lisa; Grewal, Ravnit; Pieters, Hermanus; Loos, Ben; Hoal, Eileen G.; Glashoff, Richard H.; Cornelissen, Helena; Rabie, Helena; Esser, Monika M.; Kinnear, Craig J. (BioMed Central, 2020-06-05)
      Background: The X-linked recessive primary immunodeficiency disease (PIDD) Wiskott-Aldrich syndrome (WAS) is identified by an extreme susceptibility to infections, eczema and thrombocytopenia with microplatelets. ...
    • Lamivudine monotherapy as a holding regimen for HIV-positive children 

      Patten, Gabriela; Bernheime, Jonathan; Fairlie, Lee; Rabie, Helena; Sawry, Shobna; Technau, Karl; Eley, Brian; Davies, Mary-Ann (Public Library of Science, 2018)
      Background: In resource-limited settings holding regimens, such as lamivudine monotherapy (LM), are used to manage HIV-positive children failing combination antiretroviral therapy (cART) to mitigate the risk of drug ...