Prevalence of primary papillary peritoneal neoplasia in patients with ovarian carcinoma

dc.contributor.authorLindeque, B. G.
dc.contributor.authorCronje, H. S.
dc.contributor.authorDeale, C. J. C.
dc.identifier.citationLindeque, B. G., Cronje, H. S. & Deale, C. J. C. 1985. Prevalence of primary papillary peritoneal neoplasia in patients with ovarian carcinoma. South African Medical Journal, 67(25):1005-1007.
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.descriptionThe original publication is available at
dc.description.abstractPrimary papillary peritoneal neoplasia (PPPN) is a recently recognized disease entity. Macroscopically it resembles ovarian carcinoma. On microscopic examination it also superficially resembles serous ovarian adenocarcinoma, but in PPPN the epithelial cells are single-layered and well differentiated with very rare mitoses, and numerous psammoma bodies are found. In a retrospective review of 61 consecutive patients with serous or papillary ovarian adenocarcinoma seen over a 7-year period, 4 patients with PPPN were found (6.5%). One of these patients was in clinical stage I, 2 were in stage II and 1 was in stage III. All had undergone total abdominal hysterectomy and bilateral salpingo-oophorectomy. Two of these patients received additional chemotherapy and 1 radiotherapy. After 3, 3, 8 and 4 years there were no recurrences in these patients, in contrast to a 29.1% 5-year survival rate for the other patients with serous carcinoma. Cytological examination of ascitic fluid specimens performed in 3 of the 4 patients with PPPN demonstrated the presence of highly differentiated serous tufted cells.
dc.format.extent3 p. : ill.
dc.publisherHealth and Medical Publishing Group (HMPG)
dc.subjectOvaries -- Canceren_ZA
dc.titlePrevalence of primary papillary peritoneal neoplasia in patients with ovarian carcinomaen_ZA
dc.description.versionPublishers' Version
dc.rights.holderAuthors retain copyright

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