Mesothelial reaction to asbestos and other irritants after intraperitoneal injection

SUNScholar Research Repository

Show simple item record

dc.contributor.author Engelbrecht, F. M.
dc.contributor.author Burger, B. F.
dc.date.accessioned 2011-03-18T14:57:56Z
dc.date.available 2011-03-18T14:57:56Z
dc.date.issued 1975
dc.identifier.citation Engelbrecht, F.M. & Burger B.F. 1975, Mesothelial reaction to asbestos and other irritants after intraperitoneal injection, SA Medical Journal, 49(3),87-90, http://archive.samj.org.za/
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.identifier.uri http://hdl.handle.net/10019.1/7751
dc.description Article
dc.description The original publication is available from http://www.samj.org.za
dc.description Bibliography
dc.description.abstract Ten groups of rats were injected intraperitoneally with one of the following suspensions; standard reference crocidolite; acid treated crocidolite; crocidolite + iron oxide; crocidolite + silica; iron oxide; silica; long fiber crocidolite; short fiber crocidolite; long fiber glass and short fiber glass. Two rats from each group were killed at 45, 90, 150, 240 and 330 days respectively, and the pathology induced by the different suspensions was studied histologically at each time interval. No evidence in support of the chemical induction theory of mechanical irritation theory in the pathogenesis of peritoneal mesotheliomas could be found, although all the suspensions except iron oxide caused a reactive mesothelium.
dc.format.extent p. 87-90 : ill.
dc.language.iso en_ZA
dc.publisher Health and Medical Publishing Group (HMPG)
dc.subject Rats as laboratory animals -- Experiments. en_ZA
dc.subject Rats -- Effect of intraperitoneal drug administration on en_ZA
dc.subject Foreign body reaction in rats -- Diagnosis en_ZA
dc.subject Peritoneal mesotheliomas en_ZA
dc.subject Asbestos as a carcinogen en_ZA
dc.title Mesothelial reaction to asbestos and other irritants after intraperitoneal injection
dc.type Article
dc.description.version Publishers' version
dc.rights.holder Health and Medical Publishing Group (HMPG)


Files in this item

This item appears in the following Collection(s)

Show simple item record