Disseminated tuberculosis, bone marrow necrosis and lymphoma : a case report

Date
1977
Journal Title
Journal ISSN
Volume Title
Publisher
Health & Medical Publishing Group
Abstract
Tuberculosis often complicates lymphoma, and bone marrow necrosis has been described in disseminated tuberculosis. However, the association of lymphoma, disseminated tuberculosis and bone marrow necrosis is rare. We report a patient with this triple association. After a 3-week influenza-like illness the patient was admitted to hospital semicomatose with pancytopenia and hyponatraemia. During routine examination a bone marrow trephine biopsy revealed diffuse lymphomatous infiltration with scattered necrotic foci. On Ziehl-Neelsen staining these foci exhibited numerous acid-fast bacilli. The patient subsequently died and at autopsy was found to have widely disseminated non-reactive tuberculosis.
Description
CITATION: Staples, W. G., Getaz, E. P. & Botha, D. 1977. Disseminated tuberculosis, bone marrow necrosis and lymphoma : a case report. South African Medical Journal, 52(17):680-683.
The original publication is available at http://www.samj.org.za
Keywords
Tuberculosis, Bones--Necrosis, Lymphomas
Citation
Staples, W. G., Getaz, E. P. & Botha, D. 1977. Disseminated tuberculosis, bone marrow necrosis and lymphoma : a case report. South African Medical Journal, 52(17):680-683