Modified neurosyphilis in the Cape Peninsula

Abstract

A prospective study of 148 cases of neurosyphilis revealed that 85 patients exhibited a modified 'forme fruste' of the disease. A high proportion of these patients had evidence of activity in the cerebrospinal fluid, while 6 patients have developed features which are diagnostic of neurosyphilis. During the study a significant number of active seronegative cases were diagnosed and 11 patients have deteriorated on treatment.