Isolation of a lymphadenopathy-associated virus from a patient with the acquired immune deficiency syndrome
Date
1985
Journal Title
Journal ISSN
Volume Title
Publisher
Health & Medical Publishing Group
Abstract
A virus similar to the lymphadenopathy-associated virus or human T-lymphotropic virus type III, which has been described in association with the acquired immune deficiency syndrome (AIDS) by several laboratories elsewhere in the world, was isolated from a Cape Town patient with lymphadenopathy and acquired immune deficiency. This virus has the characteristic morphogenesis and ultrastructure and its genome encodes the virus-specific p24 protein. It is T-lymphotropic and produces the characteristics cytopathic effect. It can be serially propagated in a human lymphocyte line of T4+ phenotype. This isolate is being used in diagnostic immunofluorescence assays for virus-specific antibodies.
Description
CITATION: Becker, M. L. B., Spracklen, F. H. N. & Becker, W. B. 1985. Isolation of a lymphadenopathy-associated virus from a patient with the acquired immune deficiency syndrome. South African Medical Journal, 68:144-147.
The original publication is available at http://www.samj.org.za
The original publication is available at http://www.samj.org.za
Keywords
Immunological deficiency syndromes