An analysis of DTP-associated reactions by manufacturer, batch, vaccinator, series number and infant weight

Benade, J. G. (1996)

Article

The original publication is available at http://www.samj.org.za

Article

Objectives. To determine whether two commonly used DTP batches manufactured by Rhone-Poulenc Rorer were more reactogenic than two commonly used batches manufactured by the South African Institute of Medical Research. Design. Prospective study. Setting. Six community clinics. Patients. Infants routinely scheduled for their first three DTP immunisations. Main outcome measures. Local and systemic adverse reactions following immunisation with DTP. Results. Local reactions were significantly more common with both Rhone-Poulenc Rorer products. Conclusion. All adverse reaction rates compared favourably with those reported by the Centers for Disease Control.

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