Plant sterol/sterolin supplement use in a cohort of South African HIV-infected patients : effects on immunological and virological surrogate markers

Bouic, P. J. D. ; Clark, A. ; Brittle, W. ; Lamprecht, J. H. ; Freestone, M. ; Liebenberg, R. W. (2001)

CITATION: Bouic, P. J. D. et al. 2001. Plant sterol/sterolin supplement use in a cohort of South African HIV-infected patients : effects on immunological and virological surrogate markers. South African Medical Journal, 91(10):848-850.

The original publication is available at http://www.samj.org.za

Article

It has been demonstrated that micronutrient supplementation may be an important prophylactic and therapeutic measure for HIV-1-infected patients, and is possibly one of the few potential interventions for low-income countries.' In sub-Saharan countries facing the bulk of new infections worldwide, the use of highly active antiretroviral therapy (HAART) is out of reach of most patients because of the cost in the private sector and the lack of provision of any therapies by the health departments of these countries. In recent years many groups have investigated the outcomes of this infection in patients supplemented with vitamin B2 or multivitamin supplementation including/excluding vitamin A during pregnancy.' Some studies have shown that high doses of vitamin B6 supplements were associated with improved survival of patients, while zinc supplementation was associated with poorer survival.'

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