Browsing Pulmonology by Title

Now showing items 4-17 of 17

    • The diagnostic accuracy of integrated positron emission tomography/computed tomography in the evaluation of pulmonary mass lesions in a tuberculosis-endemic area 

      Du Toit, R.; Shaw, J. A.; Irusen, E. M.; Von Groote-Bidlingmaier, F.; Warwick, J. M.; Koegelenberg, C. F. N. (Health and Medical Publishing Group, 2015)
      Background. Integrated positron emission tomography/computed tomography (PET-CT) is a well-validated modality for assessing pulmonary mass lesions and specifically for estimating risk of malignancy. Tuberculosis (TB) ...

    • Endoscopic lung volume reduction in severe emphysema 

      Koegelenberg, Coenraad Frederik N.; Theron, Johan; Bruwer, J. W.; Allwood, Brian W.; Vorster, Morne J.; Von Groote-Bidlingmaier, Florian; Dheda, Keertan (Health & Medical Publishing Group, 2015)
      ENGLISH ABSTRACT: Therapeutic options in severe emphysema are limited. Endoscopic lung volume reduction (ELVR) refers to bronchoscopically inducing volume loss to improve pulmonary mechanics and compliance, thereby reducing ...

    • Epidemiology of lower respiratory infection and pneumonia in South Africa (1997 – 2015) : a systematic review protocol 

      Roomaney, Rifqah A.; Pillay-van Wyk, Victoria; Awotiwon, Oluwatoyin F.; Dhansay, Ali; Groenewald, Pam; Joubert, Jane D.; Nglazi, Mweete D.; Nicol, Edward; Bradshaw, Debbie (BMJ Publishing Group, 2016)
      Introduction: Lower respiratory infections (LRIs) and pneumonia are among the leading causes of death worldwide, especially in children aged under 5 years, and these patterns are reflected in the South African population. ...

    • Guideline for office spirometry in adults, 2004 

      Van Schalkwyk, E. M.; Schultz, C.; Joubert, J. R.; White, N. W. (Health & Medical Publishing Group, 2004-07)
      Objective. To provide clinical guidelines for office spirometry in South Africa. Options. More stringent guidelines are required for diagnostic laboratories and research. Outcomes. To minimise variations in standard practice ...

    • The impact of an electronic clinical decision support for pulmonary embolism imaging on the efficiency of computed tomography pulmonary angiography utilisation in a resource-limited setting 

      Murthy, C.; Davis, R.; Koegelenberg, C. F. N.; Irusen, E. M.; Pitcher, R. D. (Health & Medical Publishing Group, 2016-01)
      ENGLISH SUMMARY : Background. Pulmonary embolism (PE) is associated with high morbidity and mortality. Effective intervention requires prompt diagnosis. Computed tomography pulmonary angiography (CTPA) is sensitive and ...

    • Indications for the use of bronchial thermoplasty in severe asthma 

      Dheda, Keertan; Koegelenberg, Coenraad F. N.; Esmail, Aliasgar; Irusen, Elvis; Wechsler, Michael; Niven, Rob M.; Chung, Kian Fan; Bateman, Eric D. (Health & Medical Publishing Group, 2015)
      Approximately 5% of the ~3 million asthmatics in South Africa have severe asthma that is associated with substantial morbidity, cost, absenteeism, preventable mortality, and the requirement for costly chronic medication ...

    • Lung volume reduction in chronic obstructive pulmonary disease 

      Vorster, M. J.; Koegelenberg, C. F. N. (Health & Medical Publishing Group, 2015)
      Pathognomonic features of advanced emphysema include a markedly reduced alveolar surface area due to the formation of blebs and bullae and significantly reduced elastic recoil. The aim of lung volume reduction, which can ...

    • The non-pharmacological management of COPD is a neglected area in the treatment of respiratory diseases 

      Irusen, E. M.; Plekker, D. (Health and Medical Publishing Group (HMPG), 2009-04)
      An almost uniformly neglected area of respiratory disease management is the non-pharmacological component. Most patients with chronic respiratory illnesses will lose their exercise capacity (deconditioning) as the illness ...

    • Pathogenesis of chronic obstructive pulmonary disease : an African perspective 

      Allwood, Brian; Calligaro, G . (Health & Medical Publishing Group, 2015)
      The importance of chronic obstructive pulmonary disease (COPD) as a global health problem cannot be overstated. According to the latest World Health Organization statistics (2005), 210 million people suffer from COPD ...

    • The pharmacokinetics of enteral antituberculosis drugs in patients requiring intensive care 

      Koegelenberg, C. F. N.; Nortje, A.; Lalla, U.; Enslin, A.; Irusen, E. M.; Rosenkranz, B.; Seifart, H. I.; Bolliger, C. T. (Health and Medical Publishing Group (HMPG), 2013-06)
      Background. There is a paucity of data on the pharmacokinetics of fixed-dose combination enteral antituberculosis treatment in critically ill patients. Objectives. To establish the pharmacokinetic profile of a fixed-dose ...

    • The real value of endobronchial ultrasound 

      Vorster, Morne Johan; Schubert, Pawel Tomasz; Koegelenberg, Coenraad Frederik Nicolaas (Health and Medical Publishing Group, 2015)
      Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become a standard procedure worldwide, used in conjunction with bronchoscopy to obtain biopsies for mediastinal disorders. A 67-year-old man ...

    • Recommendations for the use of bronchial thermoplasty in the management of severe asthma 

      Dheda, Keertan; Koegelenberg, Coenraad F. N.; Esmail, Aliasgar; Irusen, Elvis; Wechsler, Michael; Niven, Rob M.; Bateman, Eric D.; Chung, Kian Fan (Health & Medical Publishing Group, 2015)
      There are approximately 3 million asthma suffers in South Africa, and the national death rate is ranked as one of the highest in the world. Approximately 5% have severe asthma (uncontrolled despite being adherent on maximal ...

    • Tricyclic antidepressant overdose necessitating ICU admission 

      Koegelenberg, Coenraad F. N.; Joubert, Zirkia J.; Irusen, Elvis M. (Health and Medical Publishing Group (HMPG), 2012-05)
      Tricyclic antidepressant (TCA) overdose necessitating intensive care unit (ICU) admission remains a significant problem in the Western Cape. In this retrospective study, we reviewed the course of life-threatening TCA ...

    • Validation of a severity-of-illness score in patients with tuberculosis requiring intensive care unit admission 

      Koegelenberg, Coenraad Frederik N.; Balkema, Cecile A.; Jooste, Ynishia; Taljaard, Jantjie J.; Irusen, Elvis M. (Health & Medical Publication Group, 2015-05-27)
      Background. There is a paucity of data on the determinants of mortality due to tuberculosis (TB) in the intensive care unit (ICU). Objective. To develop a simple severity-of-illness score for use in patients with TB admitted ...