Depression and anxiety in multisomatoform disorder : prevalence and clinical predictors in primary care

dc.contributor.authorMuller, Jacqueline E.
dc.contributor.authorWentzel, Ignatius
dc.contributor.authorNel, Daniel G.
dc.contributor.authorStein, Dan J.
dc.identifier.citationMuller, J.E., Wentzel, I., Nel, D.G. & Stein, D.J. 2008. Depression and anxiety in multisomatoform disorder : prevalence and clinical predictors in primary care. South African Medical Journal, 98(6) 473-476,
dc.identifier.issn02569574 (print)
dc.identifier.issn20785135 (EISSN)
dc.descriptionThe original publication is available at
dc.description.abstractObjective. Multisomatoform disorder (MSD) is characterised by ≥3 medically inexplicable, troublesome physical symptoms, together with a ≥2-year history of somatisation. The aim of this study was to evaluate the prevalence of depressive and anxiety disorders in a South African sample MSD, and to compare demographic and clinical outcomes in those patients with and without co-morbidity. Methods. Fifty-one adult outpatients with MSD were recruited from primary care clinics in the Cape Town metropole. Participants were assessed for the presence of co-morbid depressive and anxiety disorders using the Mini Neuropsychiatric Interview-Plus (MINI-Plus). Outcomes included somatic symptom severity, disability, reported sick days and health care visits, pain experience, patient satisfaction with health services, and clinician-experienced difficulty. Results. A current co-morbid depressive disorder was present in 29.4% (N=15) of patients, and a current co-morbid anxiety disorder in 52.9% (N=27). MSD patients with a co-morbid depressive disorder (current or lifetime) had significantly higher physical symptom counts, greater functional impairment, higher unemployment rates, more clinician-reported difficulties, and more dissatisfaction with health care services than those without the disorder. A larger number of co-morbid disorders was associated with greater overall disability. Conclusion. High rates of co-morbid depressive and anxiety disorders were present in a South African sample of primary care patients with MSD. Not all patients had co-morbidity, which is consistent with the view that MSD should be viewed as an independent disorder. However, co-morbid depressive disorders were associated with increased symptom severity and functional impairment, consistent with previous reports from developing countries, emphasising the importance of comorbidity in MSD.en_ZA
dc.publisherHealth and Medical Publishing Group (HMPG)
dc.subjectMultisomatoform disorderen_ZA
dc.titleDepression and anxiety in multisomatoform disorder : prevalence and clinical predictors in primary careen_ZA
dc.description.versionPublishers' version
dc.rights.holderHealth and Medical Publishing Group (HMPG)

Files in this item


This item appears in the following Collection(s)