Now showing items 1-3 of 3
Screening of four Cyclopia (honeybush) species for putative phyto-oestrogenic activity by oestrogen receptor binding assays
(AOSIS OpenJournals, 2007)
Phyto-oestrogens mediate an oestrogenic effect through binding to the oestrogen receptor (ER) subtypes, ERα and ERβ. Four commercially available Cyclopia (honeybush) species - C. intermedia, C. subternata, C. genistoides ...
A dimer of the toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins
(Public Library of Science, 2007-08-29)
The Toll-like receptor 4 (TLR4) is a class I transmembrane receptor expressed on the surface of immune system cells. TLR4 is activated by exposure to lipopolysaccharides derived from the outer membrane of Gram negative ...
Evaluation of the phytoestrogenic activity of Cyclopia genistoides (honeybush) methanol extracts and relevant polyphenols
(American Chemical Society, 2007-04)
Unfermented C. genistoides methanol extracts of different harvestings and selected polyphenols were evaluated for phytoestrogenic activity by comparing binding to both ER subtypes, transactivation of an ERE-containing ...