Browsing Research Articles (Biochemistry) by Title
Now showing items 73-79 of 79
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Targeted NGS for species level phylogenomics : "made to measure'' or "one size fits all''?
(PeerJ, 2017)Targeted high-throughput sequencing using hybrid-enrichment offers a promising source of data for inferring multiple, meaningfully resolved, independent gene trees suitable to address challenging phylogenetic problems ... -
Targeting pathogen metabolism without collateral damage to the host
(Nature Research, 2017-01-13)The development of drugs that can inactivate disease-causing cells (e.g. cancer cells or parasites) without causing collateral damage to healthy or to host cells is complicated by the fact that many proteins are very similar ... -
Tracing regulatory routes in metabolism using generalised supply-demand analysis
(BioMed Central, 2015-12)Background: Generalised supply-demand analysis is a conceptual framework that views metabolism as a molecular economy. Metabolic pathways are partitioned into so-called supply and demand blocks that produce and consume ... -
Using bark as a heat insulation material
(North Carolina State University, College of Natural Resources, 2013)Spruce bark particles were used as an insulation fill material for the thermal insulation of a timber frame wall which was subjected to a simulated winter temperature difference between indoor and outdoor climate. The ... -
Well-positioned nucleosomes punctuate polycistronic pol II transcription units and flank silent VSG gene arrays in Trypanosoma brucei
(BioMed Central, 2017)Background The compaction of DNA in chromatin in eukaryotes allowed the expansion of genome size and coincided with significant evolutionary diversification. However, chromatin generally represses DNA function, and ... -
What goes around comes around-a comparative study of the influence of chemical modifications on the antimicrobial properties of small cyclic peptides
(MDPI, 2013)Tryptophan and arginine-rich cyclic hexapeptides of the type cyclo-RRRWFW combine high antibacterial activity with rapid cell killing kinetics, but show low toxicity in human cell lines. The peptides fulfil the structural ... -
Workflow for data analysis in experimental and computational systems biology : using Python as glue
(MDPI, 2019-07-18)ENGLISH ABSTRACT: Bottom-up systems biology entails the construction of kinetic models of cellular pathways by collecting kinetic information on the pathway components (e.g., enzymes) and collating this into a kinetic ...
