• Exome sequencing combined with semantic discovery identifies strong disease-associated candidates in a single case of relapsing remitting multiple sclerosis 

  Jalali Sefid Dashti   Kotze, Maritha   Janse Van Rensburg, Susan   Christoffels, Alan   Gamieldien, Junaid (BioMed Central, 2012-10)

  As known disease-associated variants identified through large cohort-based studies often explain only a small percentage of genetic risk in multifactorial disorders such as multiple sclerosis (MS), alternative methods ...
• Pathology supported genetic testing and treatment of cardiovascular disease in middle age for prevention of Alzheimer’s disease 

  Kotze, Maritha J.   Van Rensburg, Susan J. (SpringerLink, 2012-04)

  Chronic, multi-factorial conditions caused by a complex interaction between genetic and environmental risk factors frequently share common disease mechanisms, as evidenced by an overlap between genetic risk factors ...
• Complex patterns of genomic admixture within Southern Africa 

  Petersen, Desiree C.   Libiger, Ondrej   Tindall, Elizabeth A.   Hardie, Rae-Anne   Hannick, Linda I.   Glashoff, Richard H.   Mukerji, Mitali   Indian Genome Variation Consortium   Fernandez, Pedro   Haacke, Wilfrid   Schork, Nicholas J.   Hayes, Vanessa M. (PLOS, 2013-03)

  Within-population genetic diversity is greatest within Africa, while between-population genetic diversity is directly proportional to geographic distance. The most divergent contemporary human populations include the ...
• CYP2D6 genotyping and use of antidepressants in breast cancer patients : test development for clinical application 

  Van Der Merwe, Nicole   Bouwens, Christianne S. H.   Pienaar, Rika   Van Der Merwe, Lize   Yako, Yandiswa Y.   Geiger, Dieter H.   Kotze, Maritha J. (Springer Verlag, 2012-05)

  Approximately 25 % of clinically important drugs and numerous environmental carcinogens are metabolised by CYP2D6. Variation in the CYP2D6 gene and concomitant use of tamoxifen (TAM) with certain antidepressants may increase ...
• Mycobacterial transport medium for routine culture of fine needle aspiration biopsies 

  Wright, C. A.   Bamford, C.   Prince, Y.   Vermaak, A.   Hoek, K. G. P.   Marais, B. J.   Warren, R. M. (BMJ Publishing Group, 2010-01)

  Fine needle aspiration biopsy (FNAB) offers a simple outpatient technique for specimen collection in child tuberculosis suspects with peripheral lymphadenopathy. To perform FNAB with mycobacterial culture on an outpatient ...
• Malacoplakia of the vagina: first case report 

  Van Der Walt J. J.   Marcus P. B.   De Wet J. J.   Burger A. J. J. (HMPG, 1973-08)

  The first case of malacoplakia known to have affected the female genital tract is presented. This lesion involved the upper vagina and presented clinically as an infiltrating carcinoma. No evidence of malacoplakia of the ...
• Metastatic hepatocellular carcinoma of the heart. A case report 

  Villet W.T.   Burger E.G.   Bezuidenhout D.J.J. (HMPG, 1978)

  A metastatic tumour growing in the heart more than 2 years after total removal of the primary hepatic growth is a rare event. Jaundice as a result of bile production by the metastasis is most unusual. The primary tumour ...
• Unusual presentation of choriocarcinoma. A case report 

  Villet, W. T.   Du Toit, D .F.   Conroy, C. (Health and medical Publishing Group (HMPG), 1979-01)

  Authors report the management of a case of malignant trophoblastic disease which presented initially as a haematemesis and melaena from a gastric metastasis. The patient had had a tubal sterilization 4 years previously. ...
• Gangrene of the penis after circumcision : a report of 3 cases 

  Du Toit, D. F.   Villet, W. T. (HMPG, 1979-03)

  Three patients with gangrene of the penis after Xhosa ritual tribal circumcision are reported. A review of complications which may follow circumcision is given.
• Mucocutaneous lymph node syndrome (Kawasaki disease). A report of 2 cases 

  Van Der Merwe P.L.   Gie R.P.   Hunter J.   Mouton, S. C. E.   Schwar, G. T.   Gleeson, C. M. (HMPG, 1980-12)

  Two cases of Kawasaki disease, both with cardiac involvement. are reported in South African children and the diagnostic problems are discussed. In patient 1 an ECG showed the development of an .inferior myocardial infarction, ...
• Familial dilated (congestive) cardiomyopathy. Occurrence in two brothers and an overview of the literature 

  Przybojewski, J. Z.   Van Der Walt J. J.   Van Eeden P. J.   Tiedt F. A. C. (Health and Medical Publishing Group (HMPG), 1984)

  Two young White brothers had dilated (congestive) cardiomyopathy. The elder came to autopsy after a chronic course of congestive cardiac failure; the younger underwent repeated cardiac catheterization and transvenous right ...
• Regional clinical registry data show increased incidence of cutaneous melanoma in Cape Town 

  Jessop, S.   Stubbings, H.   Sayed, R.   Duncan-Smith, J.   Schneider, J. W.   Jordaan, H. F. (Health and Medical Publishing Group (HMPG), 2008)

  [No abstract available]
• Patogenese van murale trombi idiopatiese kardiomiopatie 

  Van der Walt, J. J. (Health and Medical Publishing Group (HMPG), 1975)

  Hearts from 32 patients with idiopathic cardiomyopathy were examined postmortem. A comparative morphological study of the human hearts and of hearts from cardiomyopathic hamsters, rabbits and baboons indicates that severe ...

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