Research Articles (Anatomical Pathology)

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Research Articles (Anatomical Pathology)


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  • Jalali Sefid Dashti   Kotze, Maritha   Janse Van Rensburg, Susan   Christoffels, Alan   Gamieldien, Junaid (BioMed Central, 2012-10)
    As known disease-associated variants identified through large cohort-based studies often explain only a small percentage of genetic risk in multifactorial disorders such as multiple sclerosis (MS), alternative methods ...
  • Kotze, Maritha J.   Van Rensburg, Susan J. (SpringerLink, 2012-04)
    Chronic, multi-factorial conditions caused by a complex interaction between genetic and environmental risk factors frequently share common disease mechanisms, as evidenced by an overlap between genetic risk factors ...
  • Petersen, Desiree C.   Libiger, Ondrej   Tindall, Elizabeth A.   Hardie, Rae-Anne   Hannick, Linda I.   Glashoff, Richard H.   Mukerji, Mitali   Indian Genome Variation Consortium   Fernandez, Pedro   Haacke, Wilfrid   Schork, Nicholas J.   Hayes, Vanessa M. (PLOS, 2013-03)
    Within-population genetic diversity is greatest within Africa, while between-population genetic diversity is directly proportional to geographic distance. The most divergent contemporary human populations include the ...
  • Van Der Merwe, Nicole   Bouwens, Christianne S. H.   Pienaar, Rika   Van Der Merwe, Lize   Yako, Yandiswa Y.   Geiger, Dieter H.   Kotze, Maritha J. (Springer Verlag, 2012-05)
    Approximately 25 % of clinically important drugs and numerous environmental carcinogens are metabolised by CYP2D6. Variation in the CYP2D6 gene and concomitant use of tamoxifen (TAM) with certain antidepressants may increase ...
  • Wright, C. A.   Bamford, C.   Prince, Y.   Vermaak, A.   Hoek, K. G. P.   Marais, B. J.   Warren, R. M. (BMJ Publishing Group, 2010-01)
    Fine needle aspiration biopsy (FNAB) offers a simple outpatient technique for specimen collection in child tuberculosis suspects with peripheral lymphadenopathy. To perform FNAB with mycobacterial culture on an outpatient ...
  • Van Der Walt J. J.   Marcus P. B.   De Wet J. J.   Burger A. J. J. (HMPG, 1973-08)
    The first case of malacoplakia known to have affected the female genital tract is presented. This lesion involved the upper vagina and presented clinically as an infiltrating carcinoma. No evidence of malacoplakia of the ...
  • Villet W.T.   Burger E.G.   Bezuidenhout D.J.J. (HMPG, 1978)
    A metastatic tumour growing in the heart more than 2 years after total removal of the primary hepatic growth is a rare event. Jaundice as a result of bile production by the metastasis is most unusual. The primary tumour ...
  • Villet, W. T.   Du Toit, D .F.   Conroy, C. (Health and medical Publishing Group (HMPG), 1979-01)
    Authors report the management of a case of malignant trophoblastic disease which presented initially as a haematemesis and melaena from a gastric metastasis. The patient had had a tubal sterilization 4 years previously. ...
  • Du Toit, D. F.   Villet, W. T. (HMPG, 1979-03)
    Three patients with gangrene of the penis after Xhosa ritual tribal circumcision are reported. A review of complications which may follow circumcision is given.
  • Van Der Merwe P.L.   Gie R.P.   Hunter J.   Mouton, S. C. E.   Schwar, G. T.   Gleeson, C. M. (HMPG, 1980-12)
    Two cases of Kawasaki disease, both with cardiac involvement. are reported in South African children and the diagnostic problems are discussed. In patient 1 an ECG showed the development of an .inferior myocardial infarction, ...
  • Przybojewski, J. Z.   Van Der Walt J. J.   Van Eeden P. J.   Tiedt F. A. C. (Health and Medical Publishing Group (HMPG), 1984)
    Two young White brothers had dilated (congestive) cardiomyopathy. The elder came to autopsy after a chronic course of congestive cardiac failure; the younger underwent repeated cardiac catheterization and transvenous right ...
  • Jessop, S.   Stubbings, H.   Sayed, R.   Duncan-Smith, J.   Schneider, J. W.   Jordaan, H. F. (Health and Medical Publishing Group (HMPG), 2008)
    [No abstract available]
  • Van der Walt, J. J. (Health and Medical Publishing Group (HMPG), 1975)
    Hearts from 32 patients with idiopathic cardiomyopathy were examined postmortem. A comparative morphological study of the human hearts and of hearts from cardiomyopathic hamsters, rabbits and baboons indicates that severe ...

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