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Effect of genetic variants in genes encoding two nuclear receptors (PXR and CAR) on efavirenz levels and treatment outcome in South African HIV-infected females

Nieuwoudt, Enid (Stellenbosch : Stellenbosch University, 2014-12)

ENGLISH ABSTRACT: Efavirenz is an antiretroviral drug used in the treatment of HIV-positive patients as part of first line triple-highly active antiretroviral therapy. Treatment response varies among individuals and adverse ...