Browsing Research Articles (Genetics) by Title
Now showing items 1-20 of 48
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Abiotic stress-induced accumulation of raffinose in Arabidopsis leaves is mediated by a single raffinose synthase (RS5, At5g40390)
(BioMed Central, 2013)Background: The sucrosylgalactoside oligosaccharide raffinose (Raf, Suc-Gal1) accumulates in Arabidopsis leaves in response to a myriad of abiotic stresses. Whilst galactinol synthases (GolS), the first committed enzyme ... -
African origin for Madagascan dogs revealed by mtDNA analysis
(Royal Society, 2016)Madagascar was one of the last major land masses to be inhabited by humans. It was initially colonized by Austronesian speaking Indonesians 1500–2000 years ago, but subsequent migration from Africa has resulted in approximately ... -
Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis : a case-control association study
(BioMed Central, 2010-06)Background: Interferon gamma is a major macrophage-activating cytokine during infection with Mycobacterium tuberculosis, the causative pathogen of tuberculosis, and its role has been well established in animal models and ... -
Assessing the control potential of aldicarb against grapevine phylloxera
(South African Society for Enology and Viticulture, 1992)Aldicarb 15 G soil treatments in vineyards were evaluated for their phylloxera control potential. A post-harvest application was made on single vines and phylloxera populations on roots were quantified using a washing and ... -
Characterization of the genetic variation present in CYP3A4 in three South African populations
(Frontiers, 2013-02)The CYP3A4 enzyme is the most abundant human cytochrome P450 (CYP) and is regarded as the most important enzyme involved in drug metabolism. Inter-individual and inter-population variability in gene expression and enzyme ... -
Chromosome 22q11 in a Xhosa schizophrenia population
(Health and Medical Publishing Group (HMPG), 2012-03)Chromosome 22q11 aberrations substantially increase the risk for developing schizophrenia. Although micro-deletions in this region have been extensively investigated in different populations across the world, little is ... -
A comparative study of selected physical and biochemical traits of wild-type and transgenic sorghum to reveal differences relevant to grain quality
(Frontiers Media, 2017)Transgenic sorghum featuring RNAi suppression of certain kafirins was developed recently, to address the problem of poor protein digestibility in the grain. However, it was not firmly established if other important quality ... -
The complete mitochondrial genome and phylogenetic position of the leopard catshark, Poroderma pantherinum
(Taylor & Francis Open, 2018)We present the first mitochondrial genome of a South African endemic catshark, Poroderma pantherinum. The complete mitogenome is 16,686 bp in length, comprising 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and ... -
Complete nucleotide sequence of a South African isolate of grapevine fanleaf virus and its associated satellite RNA
(MDPI, 2013-07)The complete sequences of RNA1, RNA2 and satellite RNA have been determined for a South African isolate of Grapevine fanleaf virus (GFLV-SACH44). The two RNAs of GFLV-SACH44 are 7,341 nucleotides (nt) and 3,816 nt in length, ... -
Confirmation of the effectiveness and genetic positions of disease resistance loci in ‘Kishmish Vatkana’ (Ren1) and ‘Villard Blanc’ (Ren3 and Rpv3)
(South African Society for Enology and Viticulture, 2018)This study aimed to validate the effectiveness and to genetically characterise the fungal disease resistance genes of ‘Kishmish Vatkana’ and ‘Villard Blanc’ in South Africa using microsatellite (SSR) markers and a ... -
Diverse exopolysaccharide producing bacteria isolated from milled sugarcane : implications for cane spoilage and sucrose yield
(Public Library of Science, 2015)Bacterial deterioration of sugarcane during harvesting and processing is correlated with significant loss of sucrose yield and the accumulation of bacterial polysaccharides. Dextran, a homoglucan produced by Leuconostoc ... -
DNA methylation and demethylation are regulated by functional DNA methyltransferases and DnTET enzymes in diuraphis noxia
(Frontiers Media, 2020)Aphids are economically important insect pests of crops worldwide. Despite resistant varieties being available, resistance is continuously challenged and eventually broken down, posing a threat to food security. In the ... -
Evidence for water deficit-induced mass increases of raffinose family oligosaccharides (RFOs) in the leaves of three Craterostigma resurrection plant species
(Frontiers Media, 2015-07)The leaves of the resurrection plant Craterostigma plantagineum accumulate sucrose during dehydration, via a conversion from the unusual C8 ketose-sugar 2-octulose. However, raffinose family oligosaccharides (RFOs) have ... -
Extending the sRNAome of Apple by next-generation sequencing
(Public Library of Science, 2014-04)The global importance of apple as a fruit crop necessitates investigations into molecular aspects of the processes that influence fruit quality and yield, including plant development, fruit ripening and disease resistance. ... -
Genome of Russian wheat aphid an economically important cereal aphid
(BioMed Central, 2017-12-28)Although the hemipterans ( Aphididae ) are comprised of roughly 50,000 extant insect species, only four have sequenced genomes that are publically available, namely ... -
Genomic and secretomic insight into lignocellulolytic system of an endophytic bacterium Pantoea ananatis Sd-1
(BioMed Central, 2016)Background: Exploring microorganisms especially bacteria associated with the degradation of lignocellulosic biomass shows great potentials in biofuels production. The rice endophytic bacterium Pantoea ananatis Sd-1 with ... -
GSA-PCA : gene set generation by principal component analysis of the Laplacian matrix of a metabolic network
(BioMed Central, 2012-08)Abstract Background Gene Set Analysis (GSA) has proven to be a useful approach to microarray analysis. However, most of the method development for GSA has focused on the statistical tests ... -
High-throughput sequencing reveals small RNAs involved in ASGV infection
(BioMed Central, 2014)Background : Plant small RNAs (sRNAs) associated with virulent virus infections have been reported by previous studies, while the involvement of sRNAs in latent virus infection remains largely uncharacterised. Apple trees ... -
In silico analysis of the grapefruit sRNAome, transcriptome and gene regulation in response to CTV-CDVd co-infection
(BioMed Central, 2017)Background: Small RNA (sRNA) associated gene regulation has been shown to play a significant role during plant-pathogen interaction. In commercial citrus orchards co-infection of Citrus tristeza virus (CTV) and viroids ... -
Introduction of the AmpliChip CYP450 Test to a South African cohort : a platform comparative prospective cohort study
(BioMed Central, 2013-01)Abstract Background Adverse drug reactions and lack of therapeutic efficacy associated with currently prescribed pharmacotherapeutics may be attributed, in part, to inter-individual variability ...
