Recent Submissions

  • Malignant peripheral nerve sheath tumours and neurofibromatosis 1 : a case series and recommendations for care 

    Burger, Henriette; Bezuidenhout, Heidre; Sher-Locketz, Candice; Baatjes, Karin; Van Wyk, Jacques; Bonthuys, Anita (AOSIS, 2018-08-20)
    Background: The incidence of malignant peripheral nerve sheath tumours (MPNST) in patients with neurofibromatosis 1 (NF1) is significantly higher than that of the general population. NF1-associated MPNST occur at a younger ...
  • Chemotherapy administration standards and guidelines : the development of a resource document 

    Eedes, David J.; Bailey, Belinda; Burger, Henriette (AOSIS, 2018-08-13)
    There are no nationally recognised guidelines for the handling and administration of chemotherapy in South Africa. The Independent Clinical Oncology Network’s Chemotherapy Administration Standards and Guidelines Resource ...
  • Hypofractionation and prostate cancer : a good option for Africa? 

    Incrocci, Luca; Heijmen, Ben; Kupelian, Patrick; Simonds, Hannah M. (AOSIS, 2017-08-29)
    Cancer is an emerging public health problem in Africa. According to the World Health Organization, the numbers will be doubled by 2030 because of the ageing and the growth of the population. Prostate cancer is the most ...
  • Radiation planning assistant - a streamlined, fully automated radiotherapy treatment planning system 

    Court, Laurence E.; Kisling, Kelly; McCarroll, Rachel; Zhang, Lifei; Yang, Jinzhong; Simonds, Hannah; Du Toit, Monique; Trauernicht, Chris; Burger, Hester; Parkes, Jeannette; Mejia, Mike; Bojador, Maureen; Balter, Peter; Branco, Daniela; Steinmann, Angela; Baltz, Garrett; Gay, Skylar; Anderson, Brian; Cardenas, Carlos; Jhingran, Anuja; Shaitelman, Simona; Bogler, Oliver; Schmeller, Kathleen; Followill, David; Howell, Rebecca; Nelson, Christopher; Peterson, Christine; Beadle, Beth (Journal of Visualized Experiments, 2018)
    The Radiation Planning Assistant (RPA) is a system developed for the fully automated creation of radiotherapy treatment plans, including volume-modulated arc therapy (VMAT) plans for patients with head/neck cancer and ...
  • Retrospective analysis of radiotherapy outcomes in breast cancer radiotherapy at a single institution 

    Heunis, M.; Lombe, D. C.; McCaulb, M. (Medpharm Publications, 2018)
    Introduction: Breast cancer is the most commonly diagnosed cancer worldwide. With the challenges of cancer treatment in developing countries there is a need for a systematic and methodical approach to treatment in ...
  • A retrospective analysis of the effect of planning tumour volume on survival in cervical carcinoma 

    Fourie, Ilze; Simonds, Hannah M. (Medpharm Publications, 2018)
    Introduction: Locally advanced stages of invasive cervical cancer (ICC) are associated with poor outcomes; factors influencing survival include increased tumour volume. In resource-constrained settings access to diagnostic ...
  • Ovarian germ cell tumour and bleomycin-induced lung injury 

    Barnardt, Pieter; Griffith-Richards, Stephanie (Medpharm Publications, 2018)
    Bleomycin, an antibiotic agent with antitumour activity, is an important drug in the management of many oncological malignancies such as lymphoma and germ cell tumours. These tumours are potentially curable and mostly ...
  • Medical students' perceptions on euthanasia and physician-assisted suicide : are they fully informed? 

    Burger, H.; Gwyther, L.; Krause, R.; Ratshikana-Moloko, M.; Hellenberg, D. (Health & Medical Publishing Group, 2018)
    No abstract available
  • Establishing a multidisciplinary AIDS-associated Kaposi’s sarcoma clinic : patient characteristics, management and outcomes 

    Burger, H.; Ismail, Z.; Taljaard, J. J. (Health & Medical Publishing Group, 2018-12)
    Background: Kaposi’s sarcoma (KS) typically occurs in the setting of immunodeficiency and specifically in the presence of HIV infection, when it is called AIDS-associated KS (AIDS-KS). In spite of impressive gains in the ...
  • Audits of oncology units – an effective and pragmatic approach 

    Abratt, R. P.; Eedes, D.; Bailey, B.; Salmon, C.; Govender, Y.; Oelofse, I.; Burger, H. (Health and Medical Publishing Group, 2017)
    Background. Audits of oncology units are part of all quality-assurance programmes. However, they do not always come across as pragmatic and helpful to staff. Objective. To report on the results of an online survey on ...
  • Gestational trophoblastic neoplasm and women living with HIV and/or AIDS 

    Barnardt, Pieter; Relling, Martha (AOSIS Publishing, 2015-07-03)
    The 2011 World Health Organization global report on HIV and/or AIDS estimated that sub-Saharan Africa comprised 67% of the global HIV burden, with a current estimate of 5.9 million cases in South Africa. Since the introduction ...
  • Primary breast lymphoma and HIV/AIDS 

    Barnardt, Pieter; Narinesingh, Dylan (AOSIS OpenJournals, 2011-09)
    Primary extranodal lymphoma of the breast is rare and accounts for 0.04 - 0.53% of all malignant tumours, less than 1% of non-Hodgkin’s lymphomas (NHLs) and 1.7% of extranodal NHLs.1 Extranodal lymphoma arises from tissue ...
  • Managing AIDS-related Kaposi’s sarcoma and pregnancy 

    Barnardt, Pieter (AOSIS Publishing, 2013-05)
    An estimated 30 - 40% of HIV-infected patients are likely to develop cancer during the progression of their disease. The occurrence of malignancy among these patients represents a difficult challenge in their care. Kaposi’s ...
  • Plasma sarcosine does not distinguish early and advanced stages of prostate cancer 

    Bohm, L.; Serafin, A. M.; Fernandez, P.; Van der Watt, G.; Bouic, P. J. D.; Harvey, J. (Health and Medical Publishing Group (HMPG), 2012-08)
    Introduction. Diagnosis of prostate cancer by prostate specific antigen (PSA) is error-prone and cannot distinguish benign prostatic hyperplasia (BPH) from malignant disease, nor identify aggressive and indolent types. ...
  • Long-term complications of pelvic radiotherapy 

    Simonds, Hannah (South African Society of Gynaecologic Oncology, 2010)
    Complications following pelvic radiation are frequently under-reported and inadequately addressed. This overview examines the nature and the intensity of complications encountered by cancer survivors; it focuses specifically ...
  • Neutron radiotherapy in South Africa : neutron radiotherapy should continue 

    Sauerwein, Wolfgang; Engenhart-Cabillic, Rita; Forman, Jeffrey D.; Gueulette, John; Hachem, Sabet; Jones, Dan; Krull, Andreas; Lukas, Peter; Mandrillon, Pierre; Petry, Winfried; Rosenberg, Ivan; Venimmen, Frederik; Welsh, James S. (Health and Medical Publishing Group (HMPG), 2012-04)
    To the Editor: Abratt’s letter needs a response. We are currently – or have been directly – involved in treating patients with fast neutrons for decades; some with more than 20 years’ experience in proton therapy, and ...
  • Rabdomiosarkoom van die blaas 

    Malan, P. J. (Health and Medical Publishing Group (HMPG), 1975-08)
    Two cases of rhabdomyosarcoma of the bladder are reported. These tumors mainly occur in male children. They may arise in any part of the bladder and usually cause dysuria, lower urinary tract obstruction and a palpable ...
  • Photosensitizers and radiosensitizers in dermatology and oncology 

    Bruckner, V. (HMPG, 1979-09)
    Two therapeutic modalities are currently of great interest, namely photo- and radiosensitization. Whereas photosensitizers only function in combination with ultraviolet (UV) light, radiosensitizers act only in combination ...
  • Morphine and chronic cancer pain 

    Smit, B. J. (Health & Medical Publishing Group, 2001-10)
    Cancer pain can be broken down into the following categories: (i),pain caused by the cancer process itself, i.e. bony invasion or nerve compression or infiltration that is likely to present with the features of acute pain; ...
  • The role of vitamin A in cancer 

    Mills, E. E. D. (Health & Medical Publishing Group, 1983)
    The differentiation and maintenance of epithelial tissues is a well-known function of vitamin A. The most dramatic expression of this is the antineoplastic effect. This biological activity of vitamin A is reviewed with ...

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