Background World Health Organization (WHO) guidelines for monitoring HIV-infected individuals taking combination antiretroviral therapy (cART) in resource-limited settings recommend using CD4þ T cell (CD4) count changes ...

Aim: To determine whether an association exists between the different plasma lipoprotein constituents and the prevalence of lenticular opacities in dyslipidaemic subjects. Methods: Adult patients (n = 115) of both genders ...

The presence of founder effects in South Africa for many single-gene diseases, which include heart diseases such as progressive familial heart block types I and II, hypertrophic cardiomyopathy and the long QT syndromes, ...

Existing solid scientific evidence with hard outcome data should be the basis for treatment guidelines, and where such evidence is lacking, we must invest in research. A case in point is the initiation of antihypertensive ...

Objectives: To compare the efficacy of intrapericardial corticosteroid therapy to either oral corticosteroid therapy or intrapericardial placebo in addition to closed pericardiocentesis and anti-tuberculous therapy in ...

Aim: To describe the abnormalities on chest X-ray (CXR) in patients presenting with tuberculous pericardial effusions. Methods: One hundred and seventy patients presented to Tygerberg Hospital with large pericardial ...

An evaluation of a 38-year-old Caucasian woman, who was referred to Tygerberg Hospital (Western Cape Province, RSA) with Wenckebach second-degree or possibly complete atrioventricular (AV) block that had progressed from ...

Objective: To evaluate left ventricular enlargement in the lateral projection of the chest using the Hoffman and Rigler sign. Background: The Hoffman and Rigler sign for determining left ventricular enlargement was suggested ...