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Now showing items 1-2 of 2

    • Insights into the evolutionary history of tubercle bacilli as disclosed by genetic rearrangements within a PE_PGRS duplicated gene pair 

      Karboul, Anis; Gey van Pittius, Nicolaas C.; Namouchi, Amine; Vincent, Veronique; Sola, Christophe; Rastogi, Nalin; Suffys, Philip; Fabre, Michel; Cataldi, Angel; Huard, Richard C.; Kurepina, Natalia; Kreiswirth, Barry; Ho, John L.; Gutierrez, M. Cristina; Mardassi, Helmi (BioMed Central, 2006-12)
      Background: The highly homologous PE_PGRS (Proline-glutamic acid_polymorphic GC-rich repetitive sequence) genes are members of the PE multigene family which is found only in mycobacteria. PE genes are particularly abundant ...

    • Translational research for tuberculosis elimination : priorities, challenges, and actions 

      Lienhardt, Christian; Lonnroth, Knut; Menzies, Dick; Balasegaram, Manica; Chakaya, Jeremiah; Cobelens, Frank; Cohn, Jennifer; Denkinger, Claudia M.; Evans, Thomas G.; Kallenius, Gunilla; Kaplan, Gilla; Kumar, Ajay M. V.; Matthiessen, Line; Mgone, Charles S.; Mizrahi, Valerie; Mukadi, Ya-diul; Nguyen, Viet Nhung; Nordstrom, Anders; Sizemore, Christine F.; Spigelman, Melvin; Squire, S. Bertel; Swaminathan, Soumya; Van Helden, Paul D.; Zumla, Alimuddin; Weyer, Karin; Weil, Diana; Raviglione, Mario (Public Library of Science, 2016)
      Summary Points: • The WHO End TB Strategy, endorsed by the World Health Assembly in May 2014, has the ambitious goal of ending the global tuberculosis (TB) epidemic by 2035, with targets of a 95% decline in deaths due ...