Now showing items 1-2 of 2

    • Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa 

      Muller, Borna; Chihota, Violet N.; Pillay, Manormoney; Klopper, Marisa; Streicher, Elizabeth M.; Coetzee, Gerrit; Trollip, Andre; Hayes, Cindy; Bosman, Marlein E.; Gey van Pittius, Nicolaas C.; Victor, Thomas C.; Gagneux, Sebastien; Van Helden, Paul D.; Warren, Robin M. (Public Library of Science, 2013-08-23)
      Background: South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized ...

    • Promoter variation in the DC-SIGN–Encoding Gene CD209 is associated with tuberculosis 

      Barreiro, Luis B.; Neyrolles, Olivier; Babb, Chantal L.; Tailleux, Ludovic; Quach, Helene; McElreavey, Ken; Van Helden, Paul D.; Hoal, Eileen G.; Gicquel, Brigitte; Quintana-Murci, Lluis (Public Library of Science (PLOS), 2006-01)
      Background Tuberculosis, which is caused by Mycobacterium tuberculosis, remains one of the leading causes of mortality worldwide. The C-type lectin DC-SIGN is known to be the major M. tuberculosis receptor on human ...