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Combinatorial treatments of tamoxifen with SM6Met, a selective estrogen receptor subtype modulator (SERSM), from Cyclopia subternata are superior to current endocrine treatments in breast cancer cell models. (Stellenbosch : Stellenbosch University, 2018-12)ENGLISH ABSTRACT: Globally and in South Africa breast cancer is the most frequent malignancy amongst women. Most breast cancers are estrogen receptor (ER) positive and requires estrogen for growth and metastasis. Adverse ...