Now showing items 1-3 of 3
The influence of 3βHSD on adrenal steroidogenesis and the factors which influence its activity
(Stellenbosch : Stellenbosch University, 2012-12)
ENGLISH ABSTRACT: This study describes: - the characterization and comparison of the enzymatic activity of both Angora and ovine 3βHSD expressed in non-steroidogenic COS-1 cells. The apparent Km and Vmax values for ...
Comparison of two CYP17 isoforms : implications for cortisol production in the South African Merino
(Stellenbosch : Stellenbosch University, 2012-03)
ENGLISH ABSTRACT: This study describes: • the comparison of the enzymatic activities of the two ovine cytochrome P450 17 - hydroxylase/17,20-lyase (CYP17) isoforms expressed in non-steroidogenic COS-1 cells. The Km and ...
The influence of dual CYP17 expression on adrenal steroidogenesis in the South African Angora Goat
(Stellenbosch : Stellenbosch University, 2008-12)
This study describes: • the cloning and sequencing of cytochrome P450 17 -hydroxylase/17,20 lyase (CYP17), 3 -hydroxysteroid dehydrogenase (3 HSD) and cytochrome b5 from the South African Angora goat; • the identification ...