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Now showing items 1-4 of 4
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Evaluating the impact of an Xpert® MTB/RIF- based TB diagnostic algorithm in a routine operational setting in Cape Town
(Stellenbosch : Stellenbosch University, 2017-03)ENGLISH SUMMARY: Decades of reliance on slow, inaccurate diagnostic tests have contributed to poor case detection and impeded tuberculosis (TB) control efforts globally. The development of an accurate, rapid molecular ... -
How can virtual implementation modelling inform the scale-up of new molecular diagnostic tools for tuberculosis?
(Stellenbosch : Stellenbosch University, 2018-03)ENGLISH ABSTRACT: The aim of this dissertation was to develop an operational model to explain why the expected increase in the number of tuberculosis (TB) cases detected was not found in our empirical study, Policy ... -
The impact of the HPTN 071 (PopART) intervention on mortality and AIDS related morbidity amongst HIV positive adults in South Africa
(Stellenbosch : Stellenbosch University, 2018-03)ENGLISH ABSTRACT: In 2015 WHO recommended antiretroviral treatment (ART) for all HIV-positive individuals regardless of CD4 count and set a target for Universal Access to ART, that >80% of HIV-positive individuals should ... -
Mathematical modelling to project the impact of interventions targeted to previously treated individuals on the trajectory of the tuberculosis epidemic in high tuberculosis prevalence settings
(Stellenbosch : Stellenbosch University, 2018-03)ENGLISH ABSTRACT: Better strategies are needed to reduce Mycobacterium tuberculosis (M.tb) transmission in tuberculosis (TB) high-incidence settings. Targeting additional control interventions towards groups at highest TB ...