Doctoral Degrees (Paediatrics and Child Health)
Recent Submissions
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Social and contextual factors affecting HIV-infected women’s feeding practices for their infants in normal practice settings : effects on growth and morbidity
(Stellenbosch : Stellenbosch University, 2016-03)ENGLISH ABSTRACT: the significant reduction in HIV transmission through breastfeeding by antiretroviral treatment guided the current recommendations favouring breastfeeding which has to be continued until 12 months of ...
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Bronchoscopic assessment and management of children presenting with clinically significant airway obstruction due to tuberculosis
(Stellenbosch : Stellenbosch University, 2015-04)ENGLISH ABSTRACT: Tuberculosis (TB) in children is a common infectious disease in the world affecting approximately 550 000 children annually and contributing to approximately 10-15% of the TB caseload. The estimate is ...
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Childhood tuberculous meningitis : challenging current management strategies
(Stellenbosch : Stellenbosch University, 2015-04)ENGLISH ABSTRACT: Tuberculous meningitis (TBM) continues to be an important cause of mortality and neurological disability in resource-limited countries. Many questions remain about the best approaches to prevent, diagnose, ...
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Hypothalamic-pituitary-adrenal axis suppression in asthmatic children on corticosteroids
(Stellenbosch : Stellenbosch University, 2013-12)ENGLISH ABSTRACT: Although the effect of inhaled corticosteroids (ICS) on the hypothalamic- pituitary-adrenal axis (HPA) has been regarded as a “benign physiological response”, a survey published in 2002 suggested that ...
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Lipoatrophy in HIV-infected children on antiretroviral therapy
(Stellenbosch : Stellenbosch University, 2013-03)ENGLISH ABSTRACT: Introduction: Lipoatrophy is a common adverse effect of stavudine and this effect is strongly dose-dependent. Stavudine remains the most commonly used paediatric antiretroviral drug in sub-Saharan Africa, ...
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Fetal alcohol syndrome in the Western Cape : craniofacial and oral manifestations : a case control study
(Stellenbosch : Stellenbosch University, 2003-12)ENGLISH ABSTRACT: Introduction: Fetal alcohol syndrome (FAS) consists of multi-system abnormalities and is caused by the excessive intake of alcohol during pregnancy. The teratogenic effect of alcohol on the human fetus ...
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The epidemiology and management of drug-resistant tuberculosis in childhood
(Stellenbosch : Stellenbosch University, 2002-12)ENGLISH ABSTRACT: Resistance to antituberculosis agents became evident soon after antituberculosis treatment was introduced for the first time. Combined drug therapy seemed to resolve this problem. Animal experimental ...
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The influence of age on the cellular immune response in patients with tuberculosis and healthy controls
(Stellenbosch : Stellenbosch University, 2002)ENGLISH ABSTRACT: Children and adults may differ in their immune function. An adequate function of the individual's immune system is crucial to the risk for development of tuberculosis (TB) after infection with Mycobacterium ...
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Community-based growth monitoring in a rural area lacking health facilities
(Stellenbosch : Stellenbosch University, 2002-12)ENGLISH ABSTRACT: A community-based growth monitoring (GM) project was established in a rural village in KwaZulu-Natal. The project is an example of community-based activities that were based on a participatory approach ...
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A comparison of synthetic surfactants : evaluation of a novel surfactant (1,2-dipalmitoyl-sn-phosphatidycholine and trehalose [C12H22O11]) and comparison with other synthetic formulations
(Stellenbosch : Stellenbosch University, 2002-12)ENGLISH ABSTRACT: The aim of this study was to test a synthetic protein-free surfactant preparation, LPM-l, with the same chemical composition as commercially available Exosurf (Glaxo Wellcome), but containing in addition, ...
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Disease dynamics in patients with drug-resistant tuberculosis residing in a high incidence community
(Stellenbosch : Stellenbosch University, 2000-12)ENGLISH ABSTRACT: Drug-resistant tuberculosis poses a threat to global tuberculosis control by the WHO DOTS strategy. Studies in the United States and Europe have shown (i) that drug-resistant tuberculosis is present ...
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Childhood intra-thoracic tuberculosis : addressing the diagnostic dilemma
(Stellenbosch : University of Stellenbosch, 2006-04)ENGLISH ABSTRACT: Children contribute little to disease transmission and the maintenance of the tuberculosis epidemic, but they constitute a significant proportion of the total tuberculosis (TB) caseload and experience ...
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