Now showing items 1-2 of 2
The (un)SAFE and RISK(y) sides of doxorubicin-induced cardiotoxicity
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Introduction The discovery of Doxorubicin in the 1960s has drastically improved the survival rates of cancer patients, however, its success is limited by dose-dependent cardiotoxicity. While much of the ...
Toxic mitochondrial effects induced by "red devil" chemotherapy
(Stellenbosch : Stellenbosch University, 2015-04)
ENGLISH ABSTRACT: Introduction: Doxorubicin (DOX), infamously known as the “red devil,” is considered the most effective antineoplastic drug utilized in oncologic practice today. However, its clinical use is hampered due ...