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Changes in acetylcholine receptor expression : neuromuscular junction morphology and associated myonuclei in BALB/C mice following muscle contusion injury
(Stellenbosch : Stellenbosch University, 2015-03)
ENGLISH ABSTRACT: Contusion injuries cause significant muscle damage, that effects skeletal muscle in its entirety, including the innervating motorneuron and the myofibre’s neuromuscular junction (NMJ). Upon injury, the ...
Proteasome Inhibitors : a novel therapy that blunt hyperglycemia-induced cardiac contractile dysfunction
(Stellenbosch : Stellenbosch University, 2015-04)
ENGLISH ABSTRACT: Diabetes is considered a major threat to human health in both developed and developing nations. Cardiovascular disease which is common in diabetic patients has increased the overall disease affliction. ...
Toxic mitochondrial effects induced by "red devil" chemotherapy
(Stellenbosch : Stellenbosch University, 2015-04)
ENGLISH ABSTRACT: Introduction: Doxorubicin (DOX), infamously known as the “red devil,” is considered the
most effective antineoplastic drug utilized in oncologic practice today. However, its clinical
use is hampered due ...