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A comparison of the effect of curcumin treatment on apoptosis, necrosis and autophagy in a MCF-7 mammary adenocarcinoma and a MCF-12A healthy mammary epithelial cell line
(Stellenbosch : University of Stellenbosch, 2009-03)
Breast cancer is currently the primary cause of cancer-related death in women
worldwide. Conventional treatments such as radiation and chemotherapy have many
deleterious and long lasting side-effects, some of which are ...
The modulation of various signal transduction pathways in colorectal carcinoma cells by docosahexaenoic acid
(Stellenbosch : University of Stellenbosch, 2006-12)
ENGLISH ABSTRACT: Introduction: The ability of different polyunsaturated fatty acids (PUFAs),
especially n-3 PUFAs, to prevent the development of cancer has been under
intense investigation the past three decades. Numerous ...
Potential for modulation of cancer-associated oxidative stress : an in vitro investigation
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH ABSTRACT: While cancer is a chronic, complex disease associated with a multitude of steps in its initiation and progression, all cancers generally have similar underlying maladaptive physiological mechanisms which ...
A matter of life or death : autophagy in the context of prolonged doxorubicin therapy
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH ABSTRACT: Introduction
Doxorubicin (DOX) is an effective treatment against a variety of cancers, and thus remains a commonly used chemotherapeutic drug. The chief side effect of DOX treatment is cardiotoxicity. ...