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Potential for modulation of cancer-associated oxidative stress : an in vitro investigation
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH ABSTRACT: While cancer is a chronic, complex disease associated with a multitude of steps in its initiation and progression, all cancers generally have similar underlying maladaptive physiological mechanisms which ...
A matter of life or death : autophagy in the context of prolonged doxorubicin therapy
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH ABSTRACT: Introduction
Doxorubicin (DOX) is an effective treatment against a variety of cancers, and thus remains a commonly used chemotherapeutic drug. The chief side effect of DOX treatment is cardiotoxicity. ...