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The (un)SAFE and RISK(y) sides of doxorubicin-induced cardiotoxicity
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Introduction
The discovery of Doxorubicin in the 1960s has drastically improved the survival rates of cancer
patients, however, its success is limited by dose-dependent cardiotoxicity. While much of the ...
Toxic mitochondrial effects induced by "red devil" chemotherapy
(Stellenbosch : Stellenbosch University, 2015-04)
ENGLISH ABSTRACT: Introduction: Doxorubicin (DOX), infamously known as the “red devil,” is considered the
most effective antineoplastic drug utilized in oncologic practice today. However, its clinical
use is hampered due ...
Does cardioprotection by autophagy go beyond acute cardiotoxicity?
(Stellenbosch : Stellenbosch University, 2016-03)
ENGLISH ABSTRACT: Introduction and Aim
The discovery of Doxorubicin (DOX) in the 1960s has drastically improved the survival rates of cancer patients; however, its success is limited by dose-dependent cardiotoxicity. While ...