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Elucidating the role of WDR47 in regulating neuronal migration, autophagy and tubulin dynamics
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Introduction Normal cerebral cortex development depends on extensive neuronal migration during
embryogenesis, permitting the formation of accurate synaptic circuits and a highly ordered
laminar neocortex. ...
A matter of life or death : autophagy in the context of prolonged doxorubicin therapy
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH ABSTRACT: Introduction
Doxorubicin (DOX) is an effective treatment against a variety of cancers, and thus remains a commonly used chemotherapeutic drug. The chief side effect of DOX treatment is cardiotoxicity. ...