Now showing items 1-3 of 3
Design and synthesis of dual-active heterocyclic yybrid inhibitors for β-Hematin and plasmodium falciparum N-Myristoyltransferase (Stellenbosch : Stellenbosch University, 2016-03)ENGLISH ABSTRACT: The current project focused on the design and synthesis of a novel antiplasmodial dual-active conjugate hybrid compound based on an indole scaffold and known antiplasmodial quinolines. The two scaffolds ...
(Stellenbosch : Stellenbosch University, 2016-12)ENGLISH ABSTRACT: A theoretical study of a series of Au(I) complexes was performed in order to evaluate their suitability as anti-cancer prodrugs targeting the mitochondria and the TrxR enzyme. The complexes studied comprise ...