SUNScholar
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Faculty of Medicine and Health Sciences
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Department of Biomedical Sciences
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Molecular Biology and Human Genetics
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Doctoral Degrees (Molecular Biology and Human Genetics)
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Now showing items 1-5 of 5

Analysis and application of evolutionary markers in the epidemiology of Mycobacterium tuberculosis

Van der Spuy, Gian Dreyer (Stellenbosch : Stellenbosch University, 2008-12)

This series of studies includes both methodological analyses, aimed at furthering our understanding of, and improving the tools used in molecular epidemiology, and investigative projects which have used these tools to add ...
Application of spoligotyping in the understanding of the dynamics of Mycobacterium tuberculosis strains in high incidence communities

Streicher, Elizabeth Maria (University of Stellenbosch. Faculty of Health Sciences. Dept. of Biomedical Sciences., 2007-03)

Tuberculosis (TB) is a global health problem and demands rigorous control management efforts. A dramatic increase in the acquisition and spread of drug resistant TB globally has been observed in recent years. A grim picture ...
The characterisation of N-Acetyltransferase (NAT) in Mycobacterium tuberculosis

Sholto-Douglas-Vernon, Carolyn (Stellenbosch : University of Stellenbosch, 2005-03)

ENGLISH ABSTRACT: A gene coding for Arylaminie N-acetyltransferase (NAT) has been found in Mycobacterium tuberculosis, the casual agent of tuberculosis (TB). N-acetyltransferase acetylates and inactivates isoniazid (INH), ...
Characterization of the interaction between acetylcholinesterase and laminin : a template for discovering redundancy

Swart, Chrisna (Stellenbosch : Stellenbosch University, 2012-03)

ENGLISH ABSTRACT: Apart from its primary function in the synaptic hydrolysis of acetylcholine, acetylcholinesterase (AChE) has been shown through in vitro demonstrations to be able to promote various non-cholinergic ...
Regulators of dormancy/viability of Mycobacterium tuberculosis inside the human macrophages

Botha, Maria Magdalena (Stellenbosch : Stellenbosch University, 2012-03)

ENGLISH ABSTRACT: The investigation was aimed to improve the understanding of the binding interactions between DevS and DevR that are implicated in the regulation of the dormancy response in Mycobacterium tuberculosis. ...