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A critical analysis of mitochondrial functioning and associated proteins in obesity-related cardiomyopathy

George, Siddiqah (Stellenbosch : Stellenbosch University, 2013-03)

ENGLISH ABSTRACT: INTRODUCTION: The mechanism behind obesity-related cardiomyopathies is at present not completely known, however, cardiac insulin resistance has been implicated as one of the main arbitrators of obesity-related ...
The effects of chronic melatonin treatment on myocardial function and ischaemia and reperfusion injury in a rat model of diet-induced obesity

Nduhirabandi, Frederic (Stellenbosch : Stellenbosch University, 2010-03)

ENGLISH ABSTRACT: Obesity is a major risk factor for ischaemic heart disease. Obesity-induced metabolic abnormalities have been associated with increased oxidative stress which may play an important role in the increased ...