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A pathologic role for angiotensin II and endothelin-1 in cardiac remodelling and ischaemia and reperfusion injury in a rat model of the metabolic syndrome

Smith, Wayne (Stellenbosch : University of Stellenbosch, 2006-03)

Introduction: Obesity, which is implicated in the development of the metabolic syndrome (MS) is reaching epidemic proportions worldwide. MS significantly increases the risk of developing cardiovascular disease, which ...
The role of protein phosphatases in myocardial ischaemia and reperfusion

Fan, Wen Jun (Stellenbosch : Stellenbosch University, 2008-03)

ENGLISH ABSTRACT: Protein kinases and phosphatases play important roles in the phosphorylation state of intracellular proteins under both physiologic and pathophysiologic conditions. Compared to the large number of studies ...