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The characterisation and expression of HIV-1 subtype C gag
(Stellenbosch : Stellenbosch University, 2002)
ENGLISH ABSTRACT: The gag gene of HIV-1 encodes for one of the major structural proteins, which
contains several conserved cytotoxic T cell (CTL) epitopes. Gag specific CTL
responses are important in controlling viral ...
Molecular identification and characterisation of rodent- and shrew-borne Hantaviruses
(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: Throughout history disease entities have been described which match the
description of diseases now known to be caused by hantaviruses; however these
viruses were first identified as the aetiologic agent ...
Respiratory pathogens in cases of Sudden Unexpected Death in Infancy (SUDI) at Tygerberg forensic pathology service mortuary
(Stellenbosch : Stellenbosch University, 2014-04)
ENGLISH ABSTRACT: Background: Sudden infant death syndrome (SIDS) is considered the second most frequent cause of infant mortality worldwide. Research specifically pertaining to SIDS is limited in the South African setting. ...
Phenotypic and functional characterization of cytotoxic T lymphocytes in HIV-1 infected South African adults
(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: In just 25 years since the first reported cases in 1981, the number of Human
Immunodeficiency virus (HIV) infected people has risen to 65 million, and over 25
million have died of acquired immunodeficiency ...
Erythrocyte apoptosis (erythroptosis) and anaemia in chronic HIV-1 infection : relationship with immune activation and viraemia
(Stellenbosch : Stellenbosch University, 2013-12)
ENGLISH ABSTRACT: Chronic HIV-1 infection is characterized by extensive inflammation/immune activation and also by anaemia. Macrophages and neutrophils produce reactive oxygen species (ROS) which can cause damage to ...