Now showing items 1-2 of 2
Ethionamide cross-and co-resistance in children with isoniazid-resistant tuberculosis
BACKGROUND: Ethionamide (ETH) is a structural analogue of isoniazid (INH). Both are pro-drugs requiring activation by separate and common enzyme pathways, which could lead to co-and/or cross-resistance. OBJECTIVE: To ...
Mycobacterium tuberculosis transmission is not related to household genotype in a setting of high endemicity
Among the different strains of Mycobacterium tuberculosis, Beijing has been identified as an emerging genotype. Enhanced transmissibility provides a potential mechanism for genotype selection. This study evaluated whether ...