Now showing items 1-6 of 6
Tuberculosis in oncology patients
Background: There is a dearth of studies addressing the incidence and clinical presentation of tuberculosis (TB) in children with cancer. Aim: To evaluate the incidence of TB in paediatric oncology patients at Tygerberg ...
Mycobacterium tuberculosis transmission is not related to household genotype in a setting of high endemicity
Among the different strains of Mycobacterium tuberculosis, Beijing has been identified as an emerging genotype. Enhanced transmissibility provides a potential mechanism for genotype selection. This study evaluated whether ...
Recurrent culture-confirmed tuberculosis in human immunodeficiency virus-infected children
Introduction: Recurrent tuberculosis (TB) is more common among human immunodeficiency virus (HIV)-infected than HIV-uninfected adults. There are limited data regarding recurrence of TB in children. Objective: To determine ...
Transmission of multidrug-resistant tuberculosis
Aim. To compare the Mycobacterium tuberculosis isolates of adult index cases with multidrug-resistant (MDR) tuberculosis to the isolates obtained from their child contacts. Patients and methods. A 4-year prospective study ...
Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis
OBJECTIVES: Animal studies point to increased virulence of certain mycobacterial strains, notably those of the Beijing genotype. There are limited data on mycobacterial genotypic diversity in children with tuberculous ...
Failure of chemoprophylaxis with standard antituberculosis agents in child contacts of multidrug-resistant tuberculosis cases
BACKGROUND: There is little published information on optimal chemoprophylaxis for children with multidrug-resistant tuberculosis (MDR-TB) contacts. Current guidelines of World Health Organization suggest that isoniazid ...