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HIV and childhood tuberculosis: The way forward
(2004)
Tuberculosis has been a major cause of morbidity and mortality in under-resourced communities. By causing progressive immunodeficiency, the human immunodeficiency virus (HIV) increases susceptibility to tuberculosis in an ...
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
(2010)
Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...
Papulonecrotic tuberculid in children: A report of eight patients
(1996)
Papulonecrotic tuberculid (PNT), a form of cutaneous tuberculosis (TB), is uncommon in children. We identified eight children (six girls and two boys) with PNT. Their ages ranged from 19 to 139 months (median: 47.5 months, ...
Resistant Mycobacterium bovis Bacillus Calmette-Guérin Disease: Implications for Management of Bacillus Calmette-Guérin Disease in Human Immunodeficiency Virus-Infected Children
(2004)
Guidelines for the diagnosis and management of Bacillus Calmette-Guérin (BCG) disease in children are lacking, and there are limited data on drug resistance of Mycobacterium bovis BCG. A 6-month-old HIV-infected infant ...
Twice weekly vs. daily chemotherapy for childhood tuberculosis
(2000)
Background. Treating childhood tuberculosis places a large burden on health services, and ways of lessening this were sought. Methods. A randomized controlled trial was conducted to determine the effectiveness of fully ...
Culture-positive tuberculosis in human immunodeficiency virus type 1- infected children
(1998)
Background. Adults infected by HIV have increased susceptibility to Mycobacterium tuberculosis and progress more rapidly to disease. HIV and tuberculosis (TB) coinfection in children has been reported but often lacks ...
Transmission of multidrug-resistant tuberculosis
(2000)
Aim. To compare the Mycobacterium tuberculosis isolates of adult index cases with multidrug-resistant (MDR) tuberculosis to the isolates obtained from their child contacts. Patients and methods. A 4-year prospective study ...
Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis
(2007)
OBJECTIVES: Animal studies point to increased virulence of certain mycobacterial strains, notably those of the Beijing genotype. There are limited data on mycobacterial genotypic diversity in children with tuberculous ...
Failure of chemoprophylaxis with standard antituberculosis agents in child contacts of multidrug-resistant tuberculosis cases
(2007)
BACKGROUND: There is little published information on optimal chemoprophylaxis for children with multidrug-resistant tuberculosis (MDR-TB) contacts. Current guidelines of World Health Organization suggest that isoniazid ...
Long-term linezolid treatment in a young child with extensively drug-resistant tuberculosis
(2009)
Treatment of extensively drug-resistant tuberculosis (XDR-TB) is a challenge. We describe a young child with pulmonary XDR-TB who did not respond to an aggressive multidrug-resistant TB treatment regimen, but was cured ...