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Now showing items 1-10 of 11
Tuberculosis exposure in HIV-exposed infants in a high-prevalence setting
(2008)
Exposure to TB was quantified by screening human immunodeficiency virus (HIV) exposed infants aged 3-4 months for an isoniazid prophylaxis study where tuberculosis (TB) exposure excluded enrolment. Seventy-seven (10.1%, ...
Childhood drug-resistant tuberculosis in the Western Cape Province of South Africa
(2006)
Aim: Continued surveillance of drug resistance amongst children presenting with culture-confirmed tuberculosis to a tertiary care hospital and to community clinics. Methods: Drug susceptibility testing for isoniazid and ...
Tuberculosis in oncology patients
(2008)
Background: There is a dearth of studies addressing the incidence and clinical presentation of tuberculosis (TB) in children with cancer. Aim: To evaluate the incidence of TB in paediatric oncology patients at Tygerberg ...
Beijing and Haarlem genotypes are overrepresented among children with drug-resistant tuberculosis in the Western Cape province of South Africa
(2006)
Drug resistance among children with culture-confirmed tuberculosis (TB) provides an accurate measure of transmitted drug resistance within the community. We describe the genotype diversity in children with culture-confirmed ...
The outcome of infants younger than 6 months requiring ventilation for pneumonia caused by Mycobacterium tuberculosis
(2008)
Introduction: The outcome of young infants (<6 months) being ventilated for respiratory failure caused by Mycobacterium tuberculosis (MTB) has not been recorded. Patients and Methods: A descriptive study of children <6 ...
Recurrent culture-confirmed tuberculosis in human immunodeficiency virus-infected children
(2005)
Introduction: Recurrent tuberculosis (TB) is more common among human immunodeficiency virus (HIV)-infected than HIV-uninfected adults. There are limited data regarding recurrence of TB in children. Objective: To determine ...
Transmission of multidrug-resistant tuberculosis
(2000)
Aim. To compare the Mycobacterium tuberculosis isolates of adult index cases with multidrug-resistant (MDR) tuberculosis to the isolates obtained from their child contacts. Patients and methods. A 4-year prospective study ...
Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis
(2007)
OBJECTIVES: Animal studies point to increased virulence of certain mycobacterial strains, notably those of the Beijing genotype. There are limited data on mycobacterial genotypic diversity in children with tuberculous ...
Failure of chemoprophylaxis with standard antituberculosis agents in child contacts of multidrug-resistant tuberculosis cases
(2007)
BACKGROUND: There is little published information on optimal chemoprophylaxis for children with multidrug-resistant tuberculosis (MDR-TB) contacts. Current guidelines of World Health Organization suggest that isoniazid ...
Long-term linezolid treatment in a young child with extensively drug-resistant tuberculosis
(2009)
Treatment of extensively drug-resistant tuberculosis (XDR-TB) is a challenge. We describe a young child with pulmonary XDR-TB who did not respond to an aggressive multidrug-resistant TB treatment regimen, but was cured ...