Now showing items 1-5 of 5
Childhood drug-resistant tuberculosis in the Western Cape Province of South Africa
Aim: Continued surveillance of drug resistance amongst children presenting with culture-confirmed tuberculosis to a tertiary care hospital and to community clinics. Methods: Drug susceptibility testing for isoniazid and ...
A critical look at the diagnostic value of culture-confirmation in childhood tuberculosis
Objectives: To describe the clinical presentation, delay in diagnosis and treatment initiation, and outcome of culture-confirmed childhood tuberculosis. Methods: Retrospective study of children < 13 years of age at Tygerberg ...
Beijing and Haarlem genotypes are overrepresented among children with drug-resistant tuberculosis in the Western Cape province of South Africa
Drug resistance among children with culture-confirmed tuberculosis (TB) provides an accurate measure of transmitted drug resistance within the community. We describe the genotype diversity in children with culture-confirmed ...
Radiographic signs and symptoms in children treated for tuberculosis: Possible implications for symptom-based screening in resource-limited settings
Background: The World Health Organization advises active tracing of children younger than 5 years old in household contact with a sputum smear-positive tuberculosis index case. This study compared radiographic disease ...
The impact of a change in bacille Calmette-Guérin vaccine policy on tuberculosis incidence in children in Cape Town, South Africa
BACKGROUND: A decision by the South African National Department of Health to change the route of administration and strain of bacille Calmette- Guérin (BCG) vaccine was implemented in Cape Town, South Africa, between July ...