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Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis

Maree F.; Hesseling A.C.; Schaaf H.S.; Marais B.J.; Beyers N.; Van Helden P.; Warren R.M.; Schoeman J.F. (2007)

OBJECTIVES: Animal studies point to increased virulence of certain mycobacterial strains, notably those of the Beijing genotype. There are limited data on mycobacterial genotypic diversity in children with tuberculous ...

Failure of chemoprophylaxis with standard antituberculosis agents in child contacts of multidrug-resistant tuberculosis cases

Sneag D.B.; Schaaf H.S.; Cotton M.F.; Zar H.J. (2007)

BACKGROUND: There is little published information on optimal chemoprophylaxis for children with multidrug-resistant tuberculosis (MDR-TB) contacts. Current guidelines of World Health Organization suggest that isoniazid ...