Now showing items 1-10 of 1099
Lymphoma - The immune system in disarray Theme for the 11th Congress of the South African Lymphoma Study Group meeting
[No abstract available]
Use of novel proteosome inhibitors as a therapeutic strategy in lymphomas current experience and emerging concepts
Precedent from preclinical experiments coupled with two pivotal phase 2 studies in myeloma has focused attention on a potential role for ubiquitin-proteasome pathway in modulating a number of events that occur commonly in ...
Effects of myo-Inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cellsEffects of myo-Inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells
myo-Inositol (mI) is a key metabolic precursor to the phospoinositide (PI) metabolic pathway as a key component of central G-protein coupled receptor signaling systems, including several subtypes of adrenergic, cholinergic, ...
The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for children at 18 months
Objective: To assess the long-term effects of in utero exposure to magnesium sulphate for children whose mothers had pre-eclampsia. Design: Assessment at 18 months of age for children whose mothers were recruited to the ...
Proximal renal tubular acidosis in pregnancy: A case report and literature review
Renal tubular acidosis is usually associated with chronic renal conditions and is rarely encountered in pregnancy. It may be inherited causing osteomalacia and rickets in children or acquired following autoimmune diseases ...
Wireless networks for surveillance, data capture and data management in the human immunodeficiency virus epidemic care and treatment programmes.
Biomedical and demographic data capture and the subsequent management of such information are critical factors in the implementation of any level of healthcare prevention and treatment program. The developing world is ...
Fatal hepatitis B infection despite immunization in an HIV-infected infant: A possible case of vaccine failure and immune reconstitution inflammatory syndrome
We report a case of hepatitis B immune reconstitution inflammatory syndrome in an 8-month-old girl with Mycobacterium tuberculosis complex and human immunodeficiency virus (HIV) co-infection. In resource-constrained ...
Erythrocyte membrane fatty acids in patients with multiple sclerosis
Background: Reports on fatty acids levels in multiple sclerosis remain inconclusive. Objective: To determine the erythrocyte membrane fatty acid levels in multiple sclerosis patients and correlate with Kurtzke Expanded ...
Selective lysis of erythrocytes infected with the trophozoite stage of Plasmodium falciparum by polyene macrolide antibiotics
The continuous increase in strains of the human malaria parasite Plasmodium falciparum resistant to most front-line antimalarial compounds is reason for grave clinical concern. The search for new drugs led us to investigate ...
The value of ultrasound examination of the lungs in predicting bronchopulmonary dysplasia
Background: Bronchopulmonary dysplasia (BPD) is one of the most serious complications of neonatal mechanical ventilation. Early diagnosis may influence treatment options such as early steroid administration. Objective: To ...