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  • Early decreased neutrophil responsiveness is related to late onset sepsis in multitrauma patients : an international cohort study 

    Groeneveld, Kathelijne M.; Koenderman, Leo; Warren, Brian L.; Jol, Saskia; Leenen, Luke P. H.; Hietbrink, Falco (Public Library of Science, 2017)
    Background: Severe trauma can lead to the development of infectious complications after several days, such as sepsis. Early identification of patients at risk will aid anticipating these complications. The aim of this ...

  • Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation 

    Paredes, Roger; Tzou, Philip L.; Van Zyl, Gert; Barrow, Geoff; Camacho, Ricardo; Carmona, Sergio; Grant, Philip M.; Gupta, Ravindra K.; Hamers, Raph L.; Harrigan, P. Richard; Jordan, Michael R.; Kantor, Rami; Katzenstein, David A.; Kuritzkes, Daniel R.; Maldarelli, Frank; Otelea, Dan; Wallis, Carole L.; Schapiro, Jonathan M.; Shafer, Robert W. (Public Library of Science, 2017)
    Introduction: HIV-1 genotypic resistance test (GRT) interpretation systems (IS) require updates as new studies on HIV-1 drug resistance are published and as treatment guidelines evolve. Methods: An expert panel was ...

  • Differential inhibition of adenylylated and deadenylylated forms of M. tuberculosis glutamine synthetase as a drug discovery platform 

    Theron, A.; Roth, R. L.; Hoppe, H.; Parkinson, C.; Van Der Westhuyzen, C. W.; Stoychev, S.; Wiid, I.; Pietersen, R. D.; Baker, B.; Kenyon, C. P. (Public Library of Science, 2017)
    Glutamine synthetase is a ubiquitous central enzyme in nitrogen metabolism that is controlled by up to four regulatory mechanisms, including adenylylation of some or all of the twelve subunits by adenylyl transferase. It ...

  • Child contact management in high tuberculosis burden countries : a mixed-methods systematic review 

    Szkwarko, Daria; Hirsch-Moverman, Yael; Du Plessis, Lienki; Du Preez, Karen; Car, Catherine; Mandalakas, Anna M. (Public Library of Science, 2017)
    s Metrics Comments Media Coverage Abstract Background Materials and methods Results Discussion Conclusions Supporting information References Reader Comments ...

  • Tensile and high cycle fatigue properties of annealed TI6AL4V (ELI) specimens produced by direct metal laser sintering 

    Malefane, Lerata Botsane; Du Preez, W. B.; Maringa, M.; Du Plessis, A. (Southern African Institute for Industrial Engineering, 2018)
    The tensile and high cycle fatigue (HCF) properties of high temperature annealed (HTA) direct metal laser sintered (DMLS) Ti6Al4V extra low interstitial (ELI) machined and polished specimens were investigated. The HTA heat ...

  • A systematic review of the due diligence stage of mergers and acquisitions : towards a conceptual framework 

    Bhagwan, Vivek; Grobbelaar, Sara (Saartjie); Bam, Wouter (Southern African Institute for Industrial Engineering, 2018)
    Organisations are under constant pressure to grow in the face of increased competition, changing conditions, and increasingly relaxed country and currency regulatory environments. In order to remain a player or an idustry ...

  • The megaproject sponsor as leader 

    Louw, Willem; Wium, Jan; Steyn, Herman; Gevers, Wim (Southern African Institute for Industrial Engineering, 2018)
    The importance of the sponsor role, including its contribution to the success or failure of a project, is widely recognised in the project management literature. References to the sponsor’s leadership, and the substantial ...

  • A conceptual framework to increase competitiveness in a biltong factory 

    Henning, Mieke; Hagedorn-Hansen, Devon; Von Leipzig, Konrad H. (Southern African Institute for Industrial Engineering, 2018)
    The global annual biltong market value was estimated at roughly R640 million to R1.1 billion in 2003. By 2015, biltong sales were reported to be more than R2.5 billion. To stay competitive as a biltong manufacturing company ...

  • Developing a challenges landscape relating to drug safety, provision, and distribution in resource-limited settings for the case of HIV/AIDS 

    Huysamen, Biance; De Kock, Imke H.; Bam, Louzanne (Southern African Institute for Industrial Engineering, 2018)
    Since 2010, pharmaceutical organisations have begun to provide drug patents in sub-Saharan Africa through the UN Medicine Patent Pool. This initiative allows any pharmaceutical manufacturer to access these patents and ...

  • Prevalence and factors associated with recent intimate partner violence and relationships between disability and depression in postpartum women in one clinic in eThekwini Municipality, South Africa 

    Gibbs, Andrew; Carpenter, Bradley; Crankshaw, Tamaryn; Hannass-Hancock, Jill; Smit, Jennifer; Tomlinson, Mark; Butler, Lisa (Public Library of Science, 2017)
    Intimate partner violence (IPV) experienced by pregnant and post-partum women has negative health effects for women, as well as the foetus, and the new-born child. In this study we sought to assess the prevalence and factors ...

  • Factors related to environmental barriers experienced by persons with and without disabilities in diverse African settings 

    Visagie, Surona; Eide, Arne H.; Dyrstad, Karin; Mannan, Hasheem; Swartz, Leslie; Schneider, Marguerite; Mji, Gubela; Munthali, Alister; Khogali, Mustafa; Van Rooy, Gert; Hem, Karl-Gerhard; MacLachlan, Malcolm (Public Library of Science, 2017)
    This paper explores differences in experienced environmental barriers between individuals with and without disabilities and the impact of additional factors on experienced environmental barriers. Data was collected in ...

  • Pilot production environments driven by digital twins 

    Lutters, E. (Southern African Institute for Industrial Engineering, 2018)
    Establishing production environments requires joint decision-making by stakeholders from many disciplines at different levels of aggregation, because of the significant, unpredictable, and risky investments involved. Pilot ...

  • Development of a discrete-event, stochastic multi-objective metaheuristic simulation optimisation suite for a commercial software package 

    Bamporiki, Toussaint Victor; Bekker, James (Southern African Institute for Industrial Engineering, 2018)
    In this paper, the authors present the development of an optimisation suite and its implementation. This paper is part of an ongoing project that aims at developing a hybrid metaheuristic optimisation suite to solve ...

  • Beyond funding : acknowledgement patterns in biomedical, natural and social sciences 

    Paul-Hus, Adele; Diaz-Faes, Adrian A.; Sainte-Marie, Maxime; Desrochers, Nadine; Costas, Rodrigo; Lariviere, Vincent (Public Library of Science, 2017)
    For the past 50 years, acknowledgments have been studied as important paratextual traces of research practices, collaboration, and infrastructure in science. Since 2008, funding acknowledgments have been indexed by Web ...

  • Hepatitis B virus infection as a neglected tropical disease 

    O'Hara, Geraldine A.; McNaughton, Anna L.; Maponga, Tongai; Jooste, Pieter; Ocama, Ponsiano; Chileng, Roma; Mokaya, Jolynne; Liyayi, Mitchell I.; Wachira, Tabitha; Gikungi, David M.; Burbridge, Lela; O'Donnel, Denise; Akiror, Connie S.; Sloan, Derek; Torimiro, Judith; Yindom, Louis Marie; Walton, Robert; Andersson, Monique; Marsh, Kevin; Newton, Robert; Matthews, Philippa C. (Public Library of Science, 2017)
    The Global Hepatitis Health Sector Strategy is aiming for “elimination of viral hepatitis as a public health threat” by 2030 [1], while enhanced elimination efforts for hepatitis are also promoted under the broader remit ...

  • Vacuum polarization energy for general backgrounds in one space dimension 

    Weigel, H. (Elsevier, 2017)
    For field theories in one time and one space dimensions we propose an efficient method to compute the vacuum polarization energy of static field configurations that do not allow a decomposition into symmetric and anti-symmetric ...

  • Consistency between SU(3) and SU(2) covariant baryon chiral perturbation theory for the nucleon mass 

    Ren, Xiu-Lei; Alvarez-Ruso, L.; Geng, Li-Sheng; Ledwig, Tim; Meng, Jie; Vacas, M. J. Vicente (Elsevier, 2017)
    Treating the strange quark mass as a heavy scale compared to the light quark mass, we perform a matching of the nucleon mass in the SU(3) sector to the two-flavor case in covariant baryon chiral perturbation theory. The ...

  • Superfluid filaments of dipolar bosons in free space 

    Cinti, Fabio; Cappellaro, Alberto; Salasnich, Luca; Macri, Tommaso (American Physical Society, 2017)
    We systematically investigate the zero temperature phase diagram of bosons interacting via dipolar interactions in three dimensions in free space via path integral Monte Carlo simulations with a few hundreds of particles ...

  • Identifiers for the 21st century : how to design, provision, and reuse persistent identifiers to maximize utility and impact of life science data 

    McMurry, Julie A.; Juty, Nick; Blomberg, Niklas; Burdett, Tony; Conlin, Tom; Conte, Nathalie; Courtot, Melanie; Deck, John; Dumontier, Michel; Fellows, Donal K.; Gonzalez-Beltran, Alejandra; Gormanns, Philipp; Grethe, Jeffrey; Hastings, Janna; Heriche, Jean-Karim; Hermjakob, Henning; Ison, Jon C.; Jimenez, Rafael C.; Jupp, Simon; Kunze, John; Laibe, Camille; Le Novere, Nicolas; Malone, James; Martin, Maria Jesus; McEntyre, Johanna R.; Morris, Chris; Muilu, Juha; Muller, Wolfgang; Rocca-Serra, Philippe; Sansone, Susanna-Assunta; Sariyar, Murat; Snoep, Jacky L.; Soiland-Reyes, Stian; Stanford, Natalie J.; Swainston, Neil; Washington, Nicole; Williams, Alan R.; Wimalaratne, Sarala M.; Winfree, Lilly M.; Wolstencroft, Katherine; Goble, Carole; Mungall, Christopher J.; Haende, Melissa A.; Parkinson, Helen (Public Library of Science, 2017)
    In many disciplines, data are highly decentralized across thousands of online databases (repositories, registries, and knowledgebases). Wringing value from such databases depends on the discipline of data science and on ...

  • Thermal decomposition analysis in a sphere of combustible materials 

    Lebelo, Ramoshweu Solomon; Makinde, Oluwole Daniel; Chinyoka, T. (Sage, 2017)
    In this article, we look at spontaneous combustion due to exothermic chemical reaction taking place within a stockpile of combustible material. The model includes mass and energy balance equations in a spherical domain. ...

  • No evidence for extensions to the standard cosmological model 

    Heavens, Alan; Fantaye, Yabebal; Sellentin, Elena; Eggers, Hans; Hosenie, Zafiirah; Kroon, Steve; Mootoovaloo, Arrykrishna (American Physical Society, 2017)
    We compute the Bayesian evidence for models considered in the main analysis of Planck cosmic microwave background data. By utilizing carefully defined nearest-neighbor distances in parameter space, we reuse the Monte Carlo ...

  • Glass transitions in monodisperse cluster-forming ensembles : vortex matter in type-1.5 superconductors 

    Diaz-Mendez, Rogelio; Mezzacapo, Fabio; Lechner, Wolfgang; Cinti, Fabio; Babaev, Egor; Pupillo, Guido (American Physical Society, 2017)
    At low enough temperatures and high densities, the equilibrium configuration of an ensemble of ultrasoft particles is a self-assembled, ordered, cluster crystal. In the present Letter, we explore the out-of-equilibrium ...

  • Solving Dirac equations on a 3D lattice with inverse Hamiltonian and spectral methods 

    Ren, Z. X.; Zhang, S. Q.; Meng, J. (American Physical Society, 2017)
    A new method to solve the Dirac equation on a 3D lattice is proposed, in which the variational collapse problem is avoided by the inverse Hamiltonian method and the fermion doubling problem is avoided by performing spatial ...

  • Self-consistent relativistic quasiparticle random-phase approximation and its applications to charge-exchange excitations 

    Niu, Z. M.; Niu, Y. F.; Liang, H. Z.; Long, W. H.; Meng, J. (American Physical Society, 2017)
    The self-consistent quasiparticle random-phase approximation (QRPA) approach is formulated in the canonical single-nucleon basis of the relativistic Hatree–Fock–Bogoliubov (RHFB) theory. This approach is applied to study ...

  • Nuclear matrix element of neutrinoless double-β decay : relativity and short-range correlations 

    Song, L. S.; Yao, J. M.; Ring, P.; Meng, J. (American Physical Society, 2017)
    Background:The discovery of neutrinoless double-β (0νββ) decay would demonstrate the nature of neutrinos, have profound implications for our understanding of matter-antimatter mystery, and solve the mass hierarchy problem ...

  • Influence of pairing correlations on the radius of neutron-rich nuclei 

    Zhang, Ying; Chen, Ying; Meng, Jie; Ring, Peter (American Physical Society, 2017)
    The influence of pairing correlations on the neutron root mean square (rms) radius of nuclei is investigated in the framework of self-consistent Skyrme Hartree-Fock-Bogoliubov calculations. The continuum is treated ...

  • ¹³⁷,¹³⁸,¹³⁹La(n,γ) cross sections constrained with statistical decay properties of ¹³⁸,¹³⁹,¹⁴⁰La nuclei 

    Kheswa, B. V.; Wiedeking, M.; Brown, J. A.; Larsen, A. C.; Goriely, S.; Guttormsen, M.; Garrote, F. L. Bello; Bernstein, L. A.; Bleuel, D. L.; Eriksen, T. K.; Giacoppo, F.; Gorgen, A.; Goldblum, B. L.; Hagen, T. W.; Koehler, P. E.; Klintefjord, M.; Malatji, K. L.; Midtbo, J. E.; Nyhus, H. T.; Papka, P.; Renstrm, T.; Rose, S. J.; Sahin, E.; Siem, S.; Tornyi, T. G. (American Physical Society, 2017)
    The nuclear level densities and γ-ray strength functions of ¹³⁸,¹³⁹,¹⁴⁰La were measured using the ¹³⁹La(³He,α), ¹³⁹La(³He,'³He), and ¹³⁹La(d,p) reactions. The particle-γ coincidences were recorded with the silicon particle ...

  • α clustering in ²⁸Si probed through the identification of high-lying 0⁺ states 

    Adsley, P.; Jenkins, D. G.; Cseh, J.; Dimitriova, S. S.; Brummer, J. W.; Li, K. C. W.; Marin-Lambarri, D. J.; Lukyanov, K.; Kheswa, N. Y.; Neveling, R.; Papka, P.; Pellegri, L.; Pesudo, V.; Pool, L. C.; Riczu, G.; Smit, F. D.; Van Zyl, J. J.; Zemlyanaya, E. (American Physical Society, 2017)
    Background: Aspects of the nuclear structure of light α-conjugate nuclei have long been associated with nuclear clustering based on α particles and heavier α-conjugate systems such as ¹²C and ¹⁶O. Such structures are ...

  • Nuclear matter properties with nucleon-nucleon forces up to fifth order in the chiral expansion 

    Hu, Jinniu; Zhang, Ying; Epelbaum, Evgeny; Meibner, Ulf G. (American Physical Society, 2017)
    The properties of nuclear matter are studied using state-of-the-art nucleon-nucleon forces up to fifth order in chiral effective field theory. The equations of state of symmetric nuclear matter and pure neutron matter are ...

  • Indirect study of the stellar ³⁴ Ar(α,p) ³⁷K reaction rate through ⁴⁰Ca(p,t) ³⁸Ca reaction measurements 

    Long, A. M.; Adachi, T.; Beard, M.; Berg, G. P. A.; Buthelezi, Z.; Carter, J.; Couder, M.; deBoer, R. J.; Fearick, R. W.; Fortsch, S. V.; Gorres, J.; Mira, J. P.; Murray, S. H. T.; Neveling, R.; Papka, P.; Smit, F. D.; Sideras-Haddad, E.; Swartz, J. A.; Talwar, R.; Usman, I. T.; Wiescher, M.; Van Zyl, J. J.; Volya, A. (American Physical Society, 2017)
    The ³⁴Ar(α,p)³⁷K reaction is believed to be one of the last in a sequence of (α,p) and (p,γ) reactions within the Tz=−1, sd-shell nuclei, known as the αp-process. This process is expected to influence the shape and rise ...

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