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Interferon-gamma release assays for the detection of Mycobacterium tuberculosis infection in children with cancer

Stefan D.C.; Dippenaar A.; Detjen A.K.; Schaaf H.S.; Marais B.J.; Kriel B.; Loebenberg L.; Walzl G.; Hesseling A.C. (2010)

SETTING: The paediatric oncology unit at Tygerberg Children's Hospital, South Africa. OBJECTIVES: To assess the use of the tuberculin skin test (TST) and two commercial interferon-gamma release assays (IGRAs) for the ...

Comparison of two active case-finding strategies for community-based diagnosis of symptomatic smear-positive tuberculosis and control of infectious tuberculosis in Harare, Zimbabwe (DETECTB): A cluster-randomised trial

Corbett E.L.; Bandason T.; Duong T.; Dauya E.; Makamure B.; Churchyard G.J.; Williams B.G.; Munyati S.S.; Butterworth A.E.; Mason P.R.; Mungofa S.; Hayes R.J. (2010)

Background Control of tuberculosis in settings with high HIV prevalence is a pressing public health priority. We tested two active case-finding strategies to target long periods of infectiousness before diagnosis, which ...

Effect of HIV infection status and Anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants

Madhi S.A.; Adrian P.; Cotton M.F.; McIntyre J.A.; Jean-Philippe P.; Meadows S.; Nachman S.; Kayhty H.; Klugman K.P.; Violari A. (2010)

Serotype-specific antibody concentration and opsonophagocytic activity (OPA) were evaluated after 3 doses of pneumococcal conjugate vaccine. Groups included human immunodeficiency virus (HIV)-positive infants with CD4+ ...

Antiretroviral treatment for children with peripartum nevirapine exposure

Palumbo, P.; Lindsey, J. C.; Hughes, M. D.; Cotton, M. F.; Bobat, R.; Meyers, T.; Bwakura-Dangarembizi, M.; Chi, B. H.; Musoke, P.; Kamthunzi, P.; Schimana, W.; Purdue, L.; Eshleman, S. H.; Abrams, E. J.; Millar, L.; Petzold, E.; Mofenson, L. M.; Jean-Philippe, P.; Violari A. (2010)

Background: Single-dose nevirapine is the cornerstone of the regimen for prevention of mother-to-child transmission of human immunodeficiency virus (HIV) in resource-limited settings, but nevirapine frequently selects for ...